N-alpha-acetyltransferase 30 (EC 2.3.1.256) (N-acetyltransferase 12) (N-acetyltransferase MAK3 homolog) (NatC catalytic subunit)
1_MAEVP 6_ PGPSS 11_ LLPPP 16_ APPAP 21_ AAVEP 26_ RCPFP 31_ AGAAL 36_ ACCSE 41_ DEEDD 46_ EEHEG 51_ GGSRS 56_ PAGGE 61_ SATVA 66_ AKGHP 71_ CLRCP 76_ QPPQE 81_ QQQLN 86_ GLISP 91_ ELRHL 96_ RAAAS 101_ LKSKV 106_ LSVAE 111_ VAATT 116_ ATPDG 121_ GPRAT 126_ ATKGA 131_ GVHSG 136_ ERPPH 141_ SLSSN 146_ ARTAV 151_ PSPVE 156_ AAAAS 161_ DPAAA 166_ RNGLA 171_ EGTEQ 176_ EEEEE 181_ DEQVR 186_ LLSSS 191_ LTADC 196_ SLRSP 201_ SGREV 206_ EPGED 211_ RTIRY 216_ VRYES 221_ ELQMP 226_ DIMRL 231_ ITKDL 236_ SEPYS 241_ IYTYR 246_ YFIHN 251_ WPQLC 256_ FLAMV 261_ GEECV 266_ GAIVC 271_ KLDMH 276_ KKMFR 281_ RGYIA 286_ MLAVD 291_ SKYRR 296_ NGIGT 301_ NLVKK 306_ AIYAM 311_ VEGDC 316_ DEVVL 321_ ETEIT 326_ NKSAL 331_ KLYEN 336_ LGFVR 341_ DKRLF 346_ RYYLN 351_ GVDAL 356_RLKLW
1: Catalytic subunit of the N-terminal acetyltransferase C (NatC) complex (PubMed:19398576, PubMed:37891180). Catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Leu-Ala and Met-Leu-Gly (PubMed:19398576, PubMed:37891180). N-terminal acetylation protects proteins from ubiquitination and degradation by the N-end rule pathway (PubMed:37891180). Necessary for the lysosomal localization and function of ARL8B sugeesting that ARL8B is a NatC substrate (PubMed:19398576)