PCNA-associated factor (Hepatitis C virus NS5A-transactivated protein 9) (HCV NS5A-transactivated protein 9) (Overexpressed in anaplastic thyroid carcinoma 1) (OEATC-1) (PCNA-associated factor of 15 kDa) (PAF15) (p15PAF) (PCNA-clamp-associated factor)
1_MVRTK 6_ ADSVP 11_ GTYRK 16_ VVAAR 21_ APRKV 26_ LGSST 31_ SATNS 36_ TSVSS 41_ RKAEN 46_ KYAGG 51_ NPVCV 56_ RPTPK 61_ WQKGI 66_ GEFFR 71_ LSPKD 76_ SEKEN 81_ QIPEE 86_ AGSSG 91_ LGKAK 96_ RKACP 101_ LQPDH 106_TNDEK
1: PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions. Also acts as a regulator of centrosome number