Signal peptidase complex subunit 2 (Microsomal signal peptidase 25 kDa subunit) (SPase 25 kDa subunit)
1_MAAAA 6_ VQGGR 11_ SGGSG 16_ GCSGA 21_ GGASN 26_ CGTGS 31_ GRSGL 36_ LDKWK 41_ IDDKP 46_ VKIDK 51_ WDGSA 56_ VKNSL 61_ DDSAK 66_ KVLLE 71_ KYKYV 76_ ENFGL 81_ IDGRL 86_ TICTI 91_ SCFFA 96_ IVALI 101_ WDYMH 106_ PFPES 111_ KPVLA 116_ LCVIS 121_ YFVMM 126_ GILTI 131_ YTSYK 136_ EKSIF 141_ LVAHR 146_ KDPTG 151_ MDPDD 156_ IWQLS 161_ SSLKR 166_ FDDKY 171_ TLKLT 176_ FISGR 181_ TKQQR 186_ EAEFT 191_ KSIAK 196_ FFDHS 201_ GTLVM 206_ DAYEP 211_ EISRL 216_ HDSLA 221_IERKI
1: Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (PubMed:34388369). Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site (By similarity)