26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit RPN7) (26S proteasome regulatory subunit S10) (Breast cancer-associated protein SGA-113M) (Phosphonoformate immuno-associated protein 4) (Proteasome regulatory particle subunit p44S10) (p42A)
1_MPLEN 6_ LEEEG 11_ LPKNP 16_ DLRIA 21_ QLRFL 26_ LSLPE 31_ HRGDA 36_ AVRDE 41_ LMAAV 46_ RDNNM 51_ APYYE 56_ ALCKS 61_ LDWQI 66_ DVDLL 71_ NKMKK 76_ ANEDE 81_ LKRLD 86_ EELED 91_ AEKNL 96_ GESEI 101_ RDAMM 106_ AKAEY 111_ LCRIG 116_ DKEGA 121_ LTAFR 126_ KTYDK 131_ TVALG 136_ HRLDI 141_ VFYLL 146_ RIGLF 151_ YMDND 156_ LITRN 161_ TEKAK 166_ SLIEE 171_ GGDWD 176_ RRNRL 181_ KVYQG 186_ LYCVA 191_ IRDFK 196_ QAAEL 201_ FLDTV 206_ STFTS 211_ YELMD 216_ YKTFV 221_ TYTVY 226_ VSMIA 231_ LERPD 236_ LREKV 241_ IKGAE 246_ ILEVL 251_ HSLPA 256_ VRQYL 261_ FSLYE 266_ CRYSV 271_ FFQSL 276_ AVVEQ 281_ EMKKD 286_ WLFAP 291_ HYRYY 296_ VREMR 301_ IHAYS 306_ QLLES 311_ YRSLT 316_ LGYMA 321_ EAFGV 326_ GVEFI 331_ DQELS 336_ RFIAA 341_ GRLHC 346_ KIDKV 351_ NEIVE 356_ TNRPD 361_ SKNWQ 366_ YQETI 371_ KKGDL 376_ LLNRV 381_QKLSR
1: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair