Condensin complex subunit 1 (Chromosome condensation-related SMC-associated protein 1) (Chromosome-associated protein D2) (hCAP-D2) (Non-SMC condensin I complex subunit D2) (XCAP-D2 homolog)
1_MAPQM 6_ YEFHL 11_ PLSPE 16_ ELLKS 21_ GGVNQ 26_ YVVQE 31_ VLSIK 36_ HLPPQ 41_ LRAFQ 46_ AAFRA 51_ QGPLA 56_ MLQHF 61_ DTIYS 66_ ILHHF 71_ RSIDP 76_ GLKED 81_ TLQFL 86_ IKVVS 91_ RHSQE 96_ LPAIL 101_ DDTTL 106_ SGSDR 111_ NAHLN 116_ ALKMN 121_ CYALI 126_ RLLES 131_ FETMA 136_ SQTNL 141_ VDLDL 146_ GGKGK 151_ KARTK 156_ AAHGF 161_ DWEEE 166_ RQPIL 171_ QLLTQ 176_ LLQLD 181_ IRHLW 186_ NHSII 191_ EEEFV 196_ SLVTG 201_ CCYRL 206_ LENPT 211_ INHQK 216_ NRPTR 221_ EAITH 226_ LLGVA 231_ LTRYN 236_ HMLSA 241_ TVKII 246_ QMLQH 251_ FEHLA 256_ PVLVA 261_ AVSLW 266_ ATDYG 271_ MKSIV 276_ GEIVR 281_ EIGQK 286_ CPQEL 291_ SRDPS 296_ GTKGF 301_ AAFLT 306_ ELAER 311_ VPAIL 316_ MSSMC 321_ ILLDH 326_ LDGEN 331_ YMMRN 336_ AVLAA 341_ MAEMV 346_ LQVLS 351_ GDQLE 356_ AAARD 361_ TRDQF 366_ LDTLQ 371_ AHGHD 376_ VNSFV 381_ RSRVL 386_ QLFTR 391_ IVQQK 396_ ALPLT 401_ RFQAV 406_ VALAV 411_ GRLAD 416_ KSVLV 421_ CKNAI 426_ QLLAS 431_ FLANN 436_ PFSCK 441_ LSDAD 446_ LAGPL 451_ QKETQ 456_ KLQEM 461_ RAQRR 466_ TAAAS 471_ AVLDP 476_ EEEWE 481_ AMLPE 486_ LKSTL 491_ QQLLQ 496_ LPQGE 501_ EEIPE 506_ QIANT 511_ ETTED 516_ VKGRI 521_ YQLLA 526_ KASYK 531_ KAIIL 536_ TREAT 541_ GHFQE 546_ SEPFS 551_ HIDPE 556_ ESEET 561_ RLLNI 566_ LGLIF 571_ KGPAA 576_ STQEK 581_ NPRES 586_ TGNMV 591_ TGQTV 596_ CKNKP 601_ NMSDP 606_ EESRG 611_ NDELV 616_ KQEML 621_ VQYLQ 626_ DAYSF 631_ SRKIT 636_ EAIGI 641_ ISKMM 646_ YENTT 651_ TVVQE 656_ VIEFF 661_ VMVFQ 666_ FGVPQ 671_ ALFGV 676_ RRMLP 681_ LIWSK 686_ EPGVR 691_ EAVLN 696_ AYRQL 701_ YLNPK 706_ GDSAR 711_ AKAQA 716_ LIQNL 721_ SLLLV 726_ DASVG 731_ TIQCL 736_ EEILC 741_ EFVQK 746_ DELKP 751_ AVTQL 756_ LWERA 761_ TEKVA 766_ CCPLE 771_ RCSSV 776_ MLLGM 781_ MARGK 786_ PEIVG 791_ SNLDT 796_ LVSIG 801_ LDEKF 806_ PQDYR 811_ LAQQV 816_ CHAIA 821_ NISDR 826_ RKPSL 831_ GKRHP 836_ PFRLP 841_ QEHRL 846_ FERLR 851_ ETVTK 856_ GFVHP 861_ DPLWI 866_ PFKEV 871_ AVTLI 876_ YQLAE 881_ GPEVI 886_ CAQIL 891_ QGCAK 896_ QALEK 901_ LEEKR 906_ TSQED 911_ PKESP 916_ AMLPT 921_ FLLMN 926_ LLSLA 931_ GDVAL 936_ QQLVH 941_ LEQAV 946_ SGELC 951_ RRRVL 956_ REEQE 961_ HKTKD 966_ PKEKN 971_ TSSET 976_ TMEEE 981_ LGLVG 986_ ATADD 991_ TEAEL 996_ IRGIC 1001_ EMELL 1006_ DGKQT 1011_ LAAFV 1016_ PLLLK 1021_ VCNNP 1026_ GLYSN 1031_ PDLSA 1036_ AASLA 1041_ LGKFC 1046_ MISAT 1051_ FCDSQ 1056_ LRLLF 1061_ TMLEK 1066_ SPLPI 1071_ VRSNL 1076_ MVATG 1081_ DLAIR 1086_ FPNLV 1091_ DPWTP 1096_ HLYAR 1101_ LRDPA 1106_ QQVRK 1111_ TAGLV 1116_ MTHLI 1121_ LKDMV 1126_ KVKGQ 1131_ VSEMA 1136_ VLLID 1141_ PEPQI 1146_ AALAK 1151_ NFFNE 1156_ LSHKG 1161_ NAIYN 1166_ LLPDI 1171_ ISRLS 1176_ DPELG 1181_ VEEEP 1186_ FHTIM 1191_ KQLLS 1196_ YITKD 1201_ KQTES 1206_ LVEKL 1211_ CQRFR 1216_ TSRTE 1221_ RQQRD 1226_ LAYCV 1231_ SQLPL 1236_ TERGL 1241_ RKMLD 1246_ NFDCF 1251_ GDKLS 1256_ DESIF 1261_ SAFLS 1266_ VVGKL 1271_ RRGAK 1276_ PEGKA 1281_ IIDEF 1286_ EQKLR 1291_ ACHTR 1296_ GLDGI 1301_ KELEI 1306_ GQAGS 1311_ QRAPS 1316_ AKKPS 1321_ TGSRY 1326_ QPLAS 1331_ TASDN 1336_ DFVTP 1341_ EPRRT 1346_ TRRHP 1351_ NTQQR 1356_ ASKKK 1361_ PKVVF 1366_ SSDES 1371_ SEEDL 1376_ SAEMT 1381_ EDETP 1386_ KKTTP 1391_ ILRAS 1396_ARRHR
1: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. May target the condensin complex to DNA via its C-terminal domain (PubMed:11136719). May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Required for decatenation of non-centromeric ultrafine DNA bridges during anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size (PubMed:27737959)