Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 (Centaurin-beta-1) (Cnt-b1)
1_MTVKL 6_ DFEEC 11_ LKDSP 16_ RFRAS 21_ IELVE 26_ AEVSE 31_ LETRL 36_ EKLLK 41_ LGTGL 46_ LESGR 51_ HYLAA 56_ SRAFV 61_ VGICD 66_ LARLG 71_ PPEPM 76_ MAECL 81_ EKFTV 86_ SLNHK 91_ LDSHA 96_ ELLDA 101_ TQHTL 106_ QQQIQ 111_ TLVKE 116_ GLRGF 121_ REARR 126_ DFWRG 131_ AESLE 136_ AALTH 141_ NAEVP 146_ RRRAQ 151_ EAEEA 156_ GAALR 161_ TARAG 166_ YRGRA 171_ LDYAL 176_ QINVI 181_ EDKRK 186_ FDIME 191_ FVLRL 196_ VEAQA 201_ THFQQ 206_ GHEEL 211_ SRLSQ 216_ YRKEL 221_ GAQLH 226_ QLVLN 231_ SAREK 236_ RDMEQ 241_ RHVLL 246_ KQKEL 251_ GGEEP 256_ EPSLR 261_ EGPGG 266_ LVMEG 271_ HLFKR 276_ ASNAF 281_ KTWSR 286_ RWFTI 291_ QSNQL 296_ VYQKK 301_ YKDPV 306_ TVVVD 311_ DLRLC 316_ TVKLC 321_ PDSER 326_ RFCFE 331_ VVSTS 336_ KSCLL 341_ QADSE 346_ RLLQL 351_ WVSAV 356_ QSSIA 361_ SAFSQ 366_ ARLDD 371_ SPRGP 376_ GQGSG 381_ HLAIG 386_ SAATL 391_ GSGGM 396_ ARGRE 401_ PGGVG 406_ HVVAQ 411_ VQSVD 416_ GNAQC 421_ CDCRE 426_ PAPEW 431_ ASINL 436_ GVTLC 441_ IQCSG 446_ IHRSL 451_ GVHFS 456_ KVRSL 461_ TLDSW 466_ EPELV 471_ KLMCE 476_ LGNVI 481_ INQIY 486_ EARVE 491_ AMAVK 496_ KPGPS 501_ CSRQE 506_ KEAWI 511_ HAKYV 516_ EKKFL 521_ TKLPE 526_ IRGRR 531_ GGRGR 536_ PRGQP 541_ PVPPK 546_ PSIRP 551_ RPGSL 556_ RSKPE 561_ PPSED 566_ LGSLH 571_ PGALL 576_ FRASG 581_ HPPSL 586_ PTMAD 591_ ALAHG 596_ ADVNW 601_ VNGGQ 606_ DNATP 611_ LIQAT 616_ AANSL 621_ LACEF 626_ LLQNG 631_ ANVNQ 636_ ADSAG 641_ RGPLH 646_ HATIL 651_ GHTGL 656_ ACLFL 661_ KRGAD 666_ LGARD 671_ SEGRD 676_ PLTIA 681_ METAN 686_ ADIVT 691_ LLRLA 696_ KMREA 701_ EAAQG 706_ QAGDE 711_ TYLDI 716_ FRDFS 721_ LMASD 726_ DPEKL 731_SRRSH
1: GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration