116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain-containing protein 2) (SNU114 homolog) (hSNU114) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa)
1_MDTDL 6_ YDEFG 11_ NYIGP 16_ ELDSD 21_ EDDDE 26_ LGRET 31_ KDLDE 36_ MDDDD 41_ DDDDV 46_ GDHDD 51_ DHPGM 56_ EVVLH 61_ EDKKY 66_ YPTAE 71_ EVYGP 76_ EVETI 81_ VQEED 86_ TQPLT 91_ EPIIK 96_ PVKTK 101_ KFTLM 106_ EQTLP 111_ VTVYE 116_ MDFLA 121_ DLMDN 126_ SELIR 131_ NVTLC 136_ GHLHH 141_ GKTCF 146_ VDCLI 151_ EQTHP 156_ EIRKR 161_ YDQDL 166_ CYTDI 171_ LFTEQ 176_ ERGVG 181_ IKSTP 186_ VTVVL 191_ PDTKG 196_ KSYLF 201_ NIMDT 206_ PGHVN 211_ FSDEV 216_ TAGLR 221_ ISDGV 226_ VLFID 231_ AAEGV 236_ MLNTE 241_ RLIKH 246_ AVQER 251_ LAVTV 256_ CINKI 261_ DRLIL 266_ ELKLP 271_ PTDAY 276_ YKLRH 281_ IVDEV 286_ NGLIS 291_ MYSTD 296_ ENLIL 301_ SPLLG 306_ NVCFS 311_ SSQYS 316_ ICFTL 321_ GSFAK 326_ IYADT 331_ FGDIN 336_ YQEFA 341_ KRLWG 346_ DIYFN 351_ PKTRK 356_ FTKKA 361_ PTSSS 366_ QRSFV 371_ EFILE 376_ PLYKI 381_ LAQVV 386_ GDVDT 391_ SLPRT 396_ LDELG 401_ IHLTK 406_ EELKL 411_ NIRPL 416_ LRLVC 421_ KKFFG 426_ EFTGF 431_ VDMCV 436_ QHIPS 441_ PKVGA 446_ KPKIE 451_ HTYTG 456_ GVDSD 461_ LGEAM 466_ SDCDP 471_ DGPLM 476_ CHTTK 481_ MYSTD 486_ DGVQF 491_ HAFGR 496_ VLSGT 501_ IHAGQ 506_ PVKVL 511_ GENYT 516_ LEDEE 521_ DSQIC 526_ TVGRL 531_ WISVA 536_ RYHIE 541_ VNRVP 546_ AGNWV 551_ LIEGV 556_ DQPIV 561_ KTATI 566_ TEPRG 571_ NEEAQ 576_ IFRPL 581_ KFNTT 586_ SVIKI 591_ AVEPV 596_ NPSEL 601_ PKMLD 606_ GLRKV 611_ NKSYP 616_ SLTTK 621_ VEESG 626_ EHVIL 631_ GTGEL 636_ YLDCV 641_ MHDLR 646_ KMYSE 651_ IDIKV 656_ ADPVV 661_ TFCET 666_ VVETS 671_ SLKCF 676_ AETPN 681_ KKNKI 686_ TMIAE 691_ PLEKG 696_ LAEDI 701_ ENEVV 706_ QITWN 711_ RKKLG 716_ EFFQT 721_ KYDWD 726_ LLAAR 731_ SIWAF 736_ GPDAT 741_ GPNIL 746_ VDDTL 751_ PSEVD 756_ KALLG 761_ SVKDS 766_ IVQGF 771_ QWGTR 776_ EGPLC 781_ DELIR 786_ NVKFK 791_ ILDAV 796_ VAQEP 801_ LHRGG 806_ GQIIP 811_ TARRV 816_ VYSAF 821_ LMATP 826_ RLMEP 831_ YYFVE 836_ VQAPA 841_ DCVSA 846_ VYTVL 851_ ARRRG 856_ HVTQD 861_ APIPG 866_ SPLYT 871_ IKAFI 876_ PAIDS 881_ FGFET 886_ DLRTH 891_ TQGQA 896_ FSLSV 901_ FHHWQ 906_ IVPGD 911_ PLDKS 916_ IVIRP 921_ LEPQP 926_ APHLA 931_ REFMI 936_ KTRRR 941_ KGLSE 946_ DVSIS 951_ KFFDD 956_ PMLLE 961_ LAKQD 966_VVLNY
1: Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes (PubMed:25092792, PubMed:28076346, PubMed:28502770, PubMed:28781166, PubMed:29301961, PubMed:29360106, PubMed:29361316, PubMed:30315277, PubMed:30705154). Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome (PubMed:16723661). As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable)