IQ calmodulin-binding motif-containing protein 1 (Nephrocystin-5) (p53 and DNA damage-regulated IQ motif protein) (PIQ)
1_MKPTG 6_ TDPRI 11_ LSIAA 16_ EVAKS 21_ PEQNV 26_ PVILL 31_ KLKEI 36_ INITP 41_ LGSSE 46_ LKKIK 51_ QDIYC 56_ YDLIQ 61_ YCLLV 66_ LSQDY 71_ SRIQG 76_ GWTTI 81_ SQLTQ 86_ ILSHC 91_ CVGLE 96_ PGEDA 101_ EEFYN 106_ ELLPS 111_ AAENF 116_ LVLGR 121_ QLQTC 126_ FINAA 131_ KAEEK 136_ DELLH 141_ FFQIV 146_ TDSLF 151_ WLLGG 156_ HVELI 161_ QNVLQ 166_ SDHFL 171_ HLLQA 176_ DNVQI 181_ GSAVM 186_ MMLQN 191_ ILQIN 196_ SGDLL 201_ RIGRK 206_ ALYSI 211_ LDEVI 216_ FKLFS 221_ TPSPV 226_ IRSTA 231_ TKLLL 236_ LMAES 241_ HQEIL 246_ ILLRQ 251_ STCYK 256_ GLRRL 261_ LSKQE 266_ TGTEF 271_ SQELR 276_ QLVGL 281_ LSPMV 286_ YQEVE 291_ EQKLH 296_ QAACL 301_ IQAYW 306_ KGFQT 311_ RKRLK 316_ KLPSA 321_ VIALQ 326_ RSFRS 331_ KRSKM 336_ LLEIN 341_ RQKEE 346_ EDLKL 351_ QLQLQ 356_ RQRAM 361_ RLSRE 366_ LQLSM 371_ LEIVH 376_ PGQVE 381_ KHYRE 386_ MEEKS 391_ ALIIQ 396_ KHWRG 401_ YRERK 406_ NFHQQ 411_ RQSLI 416_ EYKAA 421_ VTLQR 426_ AALKF 431_ LAKCR 436_ KKKKL 441_ FAPWR 446_ GLQEL 451_ TDARR 456_ VELKK 461_ RVDDY 466_ VRRHL 471_ GSPMS 476_ DVVSR 481_ ELHAQ 486_ AQERL 491_ QHYFM 496_ GRALE 501_ ERAQQ 506_ HREAL 511_ IAQIS 516_ TNVEQ 521_ LMKAP 526_ SLKEA 531_ EGKEP 536_ ELFLS 541_ RSRPV 546_ AAKAK 551_ QAHLT 556_ TLKHI 561_ QAPWW 566_ KKLGE 571_ ESGDE 576_ IDVPK 581_ DELSI 586_ ELENL 591_FIGGT
1: Involved in ciliogenesis. The function in an early step in cilia formation depends on its association with CEP290/NPHP6 (PubMed:21565611, PubMed:23446637). Involved in regulation of the BBSome complex integrity, specifically for presence of BBS2 and BBS5 in the complex, and in ciliary targeting of selected BBSome cargos. May play a role in controlling entry of the BBSome complex to cilia possibly implicating CEP290/NPHP6 (PubMed:25552655)