Kinesin-like protein KIF14
1_MSLHS 6_ THNRN 11_ NSGDI 16_ LDIPS 21_ SQNSS 26_ SLNAL 31_ THSSR 36_ LKLHL 41_ KSDMS 46_ ECEND 51_ DPLLR 56_ SAGKV 61_ RDINR 66_ TYVIS 71_ ASRKT 76_ ADMPL 81_ TPNPV 86_ GRLAL 91_ QRRTT 96_ RNKES 101_ SLLVS 106_ ELEDT 111_ TEKTA 116_ ETRLT 121_ LQRRA 126_ KTDSA 131_ EKWKT 136_ AEIDS 141_ VKMTL 146_ NVGGE 151_ TENNG 156_ VSKES 161_ RTNVR 166_ IVNNA 171_ KNSFV 176_ ASSVP 181_ LDEDP 186_ QVIEM 191_ MADKK 196_ YKETF 201_ SAPSR 206_ ANENV 211_ ALKYS 216_ SNRPP 221_ IASLS 226_ QTEVV 231_ RSGHL 236_ TTKPT 241_ QSKLD 246_ IKVLG 251_ TGNLY 256_ HRSIG 261_ KEIAK 266_ TSNKF 271_ GSLEK 276_ RTPTK 281_ CTTEH 286_ KLTTK 291_ CSLPQ 296_ LKSPA 301_ PSILK 306_ NRMSN 311_ LQVKQ 316_ RPKSS 321_ FLANK 326_ QERSA 331_ ENTIL 336_ PEEET 341_ VVQNT 346_ SAGKD 351_ PLKVE 356_ NSQVT 361_ VAVRV 366_ RPFTK 371_ REKIE 376_ KASQV 381_ VFMSG 386_ KEITV 391_ EHPDT 396_ KQVYN 401_ FIYDV 406_ SFWSF 411_ DECHP 416_ HYASQ 421_ TTVYE 426_ KLAAP 431_ LLERA 436_ FEGFN 441_ TCLFA 446_ YGQTG 451_ SGKSY 456_ TMMGF 461_ SEEPG 466_ IIPRF 471_ CEDLF 476_ SQVAR 481_ KQTQE 486_ VSYHI 491_ EMSFF 496_ EVYNE 501_ KIHDL 506_ LVCKD 511_ ENGQR 516_ KQPLR 521_ VREHP 526_ VYGPY 531_ VEALS 536_ MNIVS 541_ SYADI 546_ QSWLE 551_ LGNKQ 556_ RATAA 561_ TGMND 566_ KSSRS 571_ HSVFT 576_ LVMTQ 581_ TKTEF 586_ VEGEE 591_ HDHRI 596_ TSRIN 601_ LIDLA 606_ GSERC 611_ STAHT 616_ NGDRL 621_ KEGVS 626_ INKSL 631_ LTLGK 636_ VISAL 641_ SEQAN 646_ QRSVF 651_ IPYRE 656_ SVLTW 661_ LLKES 666_ LGGNS 671_ KTAMI 676_ ATISP 681_ AASNI 686_ EETLS 691_ TLRYA 696_ NQARL 701_ IVNIA 706_ KVNED 711_ MNAKL 716_ IRELK 721_ AEIAK 726_ LKAAQ 731_ RNSRN 736_ IDPER 741_ YRLCR 746_ QEITS 751_ LRMKL 756_ HQQER 761_ DMAEM 766_ QRVWK 771_ EKFEQ 776_ AEKRK 781_ LQETK 786_ ELQKA 791_ GIMFQ 796_ MDNHL 801_ PNLVN 806_ LNEDP 811_ QLSEM 816_ LLYMI 821_ KEGTT 826_ TVGKY 831_ KPNSS 836_ HDIQL 841_ SGVLI 846_ ADDHC 851_ TIKNF 856_ GGTVS 861_ IIPVG 866_ EAKTY 871_ VNGKH 876_ ILEIT 881_ VLRHG 886_ DRVIL 891_ GGDHY 896_ FRFNH 901_ PVEVQ 906_ KGKRP 911_ SGRDT 916_ PISEG 921_ PKDFE 926_ FAKNE 931_ LLMAQ 936_ RSQLE 941_ AEIKE 946_ AQLKA 951_ KEEMM 956_ QGIQI 961_ AKEMA 966_ QQELS 971_ SQKAA 976_ YESKI 981_ KALEA 986_ ELREE 991_ SQRKK 996_ MQEIN 1001_ NQKAN 1006_ HKIEE 1011_ LEKAK 1016_ QHLEQ 1021_ EIYVN 1026_ KKRLE 1031_ METLA 1036_ TKQAL 1041_ EDHSI 1046_ RHARI 1051_ LEALE 1056_ TEKQK 1061_ IAKEV 1066_ QILQQ 1071_ NRNNR 1076_ DKTFT 1081_ VQTTW 1086_ SSMKL 1091_ SMMIQ 1096_ EANAI 1101_ SSKLK 1106_ TYYVF 1111_ GRHDI 1116_ SDKSS 1121_ SDTSI 1126_ RVRNL 1131_ KLGIS 1136_ TFWSL 1141_ EKFES 1146_ KLAAM 1151_ KELYE 1156_ SNGSN 1161_ RGEDA 1166_ FCDPE 1171_ DEWEP 1176_ DITDA 1181_ PVSSL 1186_ SRRRS 1191_ RSLMK 1196_ NRRIS 1201_ GCLHD 1206_ IQVHP 1211_ IKNLH 1216_ SSHSS 1221_ GLMDK 1226_ SSTIY 1231_ SNSAE 1236_ SFLPG 1241_ ICKEL 1246_ IGSSL 1251_ DFFGQ 1256_ SYDEE 1261_ RTIAD 1266_ SLINS 1271_ FLKIY 1276_ NGLFA 1281_ ISKAH 1286_ EEQDE 1291_ ESQDN 1296_ LFSSD 1301_ RAIQS 1306_ LTIQT 1311_ ACAFE 1316_ QLVVL 1321_ MKHWL 1326_ SDLLP 1331_ CTNIA 1336_ RLEDE 1341_ LRQEV 1346_ KKLGG 1351_ YLQLF 1356_ LQGCC 1361_ LDISS 1366_ MIKEA 1371_ QKNAI 1376_ QIVQQ 1381_ AVKYV 1386_ GQLAV 1391_ LKGSK 1396_ LHFLE 1401_ NGNNK 1406_ AASVQ 1411_ EEFMD 1416_ AVCDG 1421_ VGLGM 1426_ KILLD 1431_ SGLEK 1436_ AKELQ 1441_ HELFR 1446_ QCTKN 1451_ EVTKE 1456_ MKTNA 1461_ MGLIR 1466_ SLENI 1471_ FAESK 1476_ IKSFR 1481_ RQVQE 1486_ ENFEY 1491_ QDFKR 1496_ MVNRA 1501_ PEFLK 1506_ LKHCL 1511_ EKAIE 1516_ IIISA 1521_ LKGCH 1526_ SDINL 1531_ LQTCV 1536_ ESIRN 1541_ LASDF 1546_ YSDFS 1551_ VPSTS 1556_ VGSYE 1561_ SRVTH 1566_ IVHQE 1571_ LESLA 1576_ KSLLF 1581_ CFESE 1586_ ESPDL 1591_ LKPWE 1596_ TYNQN 1601_ TKEEH 1606_ QQSKS 1611_ SGIDG 1616_ SKNKG 1621_ VPKRV 1626_ YELHG 1631_ SSPAV 1636_ SSEEC 1641_TPSRI
1: Microtubule motor protein that binds to microtubules with high affinity through each tubulin heterodimer and has an ATPase activity (By similarity). Plays a role in many processes like cell division, cytokinesis and also in cell proliferation and apoptosis (PubMed:16648480, PubMed:24784001). During cytokinesis, targets to central spindle and midbody through its interaction with PRC1 and CIT respectively (PubMed:16431929). Regulates cell growth through regulation of cell cycle progression and cytokinesis (PubMed:24854087). During cell cycle progression acts through SCF-dependent proteasomal ubiquitin-dependent protein catabolic process which controls CDKN1B degradation, resulting in positive regulation of cyclins, including CCNE1, CCND1 and CCNB1 (PubMed:24854087). During late neurogenesis, regulates the cerebellar, cerebral cortex and olfactory bulb development through regulation of apoptosis, cell proliferation and cell division (By similarity). Also is required for chromosome congression and alignment during mitotic cell cycle process (PubMed:15843429). Regulates cell spreading, focal adhesion dynamics, and cell migration through its interaction with RADIL resulting in regulation of RAP1A-mediated inside-out integrin activation by tethering RADIL on microtubules (PubMed:23209302)