Inactive phospholipase C-like protein 1 (PLC-L1) (Phospholipase C-deleted in lung carcinoma) (Phospholipase C-related but catalytically inactive protein) (PRIP)
1_MAEGA 6_ AGRED 11_ PAPPD 16_ AAGGE 21_ DDPRV 26_ GPDAA 31_ GDCVT 36_ AASGG 41_ RMRDR 46_ RSGVA 51_ LPGAA 56_ GTPAD 61_ SEAGL 66_ LEAAR 71_ ATPRR 76_ SSIIK 81_ DPSNQ 86_ KCGGR 91_ KKTVS 96_ FSSMP 101_ SEKKI 106_ SSAND 111_ CISFM 116_ QAGCE 121_ LKKVR 126_ PNSRI 131_ YNRFF 136_ TLDTD 141_ LQALR 146_ WEPSK 151_ KDLEK 156_ AKLDI 161_ SAIKE 166_ IRLGK 171_ NTETF 176_ RNNGL 181_ ADQIC 186_ EDCAF 191_ SILHG 196_ ENYES 201_ LDLVA 206_ NSADV 211_ ANIWV 216_ SGLRY 221_ LVSRS 226_ KQPLD 231_ FMEGN 236_ QNTPR 241_ FMWLK 246_ TVFEA 251_ ADVDG 256_ NGIML 261_ EDTSV 266_ ELIKQ 271_ LNPTL 276_ KEAKI 281_ RLKFK 286_ EIQKS 291_ KEKLT 296_ TRVTE 301_ EEFCE 306_ AFCEL 311_ CTRPE 316_ VYFLL 321_ VQISK 326_ NKEYL 331_ DANDL 336_ MLFLE 341_ AEQGV 346_ THITE 351_ DICLD 356_ IIRRY 361_ ELSEE 366_ GRQKG 371_ FLAID 376_ GFTQY 381_ LLSSE 386_ CDIFD 391_ PEQKK 396_ VAQDM 401_ TQPLS 406_ HYYIN 411_ ASHNT 416_ YLIED 421_ QFRGP 426_ ADING 431_ YIRAL 436_ KMGCR 441_ SVELD 446_ VSDGS 451_ DNEPI 456_ LCNRN 461_ NMTTH 466_ VSFRS 471_ VIEVI 476_ NKFAF 481_ VASEY 486_ PLILC 491_ LGNHC 496_ SLPQQ 501_ KVMAQ 506_ QMKKV 511_ FGNKL 516_ YTEAP 521_ LPSES 526_ YLPSP 531_ EKLKR 536_ MIIVK 541_ GKKLP 546_ SDPDV 551_ LEGEV 556_ TDEDE 561_ EAEMS 566_ RRMSV 571_ DYNGE 576_ QKQIR 581_ LCREL 586_ SDLVS 591_ ICKSV 596_ QYRDF 601_ ELSMK 606_ SQNYW 611_ EMCSF 616_ SETEA 621_ SRIAN 626_ EYPED 631_ FVNYN 636_ KKFLS 641_ RIYPS 646_ AMRID 651_ SSNLN 656_ PQDFW 661_ NCGCQ 666_ IVAMN 671_ FQTPG 676_ PMMDL 681_ HTGWF 686_ LQNGG 691_ CGYVL 696_ RPSIM 701_ RDEVS 706_ YFSAN 711_ TKGIL 716_ PGVSP 721_ LALHI 726_ KIISG 731_ QNFPK 736_ PKGAC 741_ AKGDV 746_ IDPYV 751_ CIEIH 756_ GIPAD 761_ CSEQR 766_ TKTVQ 771_ QNSDN 776_ PIFDE 781_ TFEFQ 786_ VNLPE 791_ LAMIR 796_ FVVLD 801_ DDYIG 806_ DEFIG 811_ QYTIP 816_ FECLQ 821_ PGYRH 826_ VPLRS 831_ FVGDI 836_ MEHVT 841_ LFVHI 846_ AITNR 851_ SGGGK 856_ AQKRS 861_ LSVRM 866_ GKKVR 871_ EYTML 876_ RNIGL 881_ KTIDD 886_ IFKIA 891_ VHPLR 896_ EAIDM 901_ RENMQ 906_ NAIVS 911_ IKELC 916_ GLPPI 921_ ASLKQ 926_ CLLTL 931_ SSRLI 936_ TSDNT 941_ PSVSL 946_ VMKDS 951_ FPYLE 956_ PLGAI 961_ PDVQK 966_ KMLTA 971_ YDLMI 976_ QESRF 981_ LIEMA 986_ DTVQE 991_ KIVQC 996_ QKAGM 1001_ EFHEE 1006_ LHNLG 1011_ AKEGL 1016_ KGRKL 1021_ NKATE 1026_ SFAWN 1031_ ITVLK 1036_ GQGDL 1041_ LKNAK 1046_ NEAIE 1051_ NMKQI 1056_ QLACL 1061_ SCGLS 1066_ KAPSS 1071_ SAEAK 1076_ SKRSL 1081_ EAIEE 1086_KESSE
1: Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor (By similarity). Regulates the turnover of receptors and thus contributes to the maintenance of GABA-mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as an inhibitor of PPP1C