Gene name: PMVK

Uniprot entry:

Q15126

Protein names:

Phosphomevalonate kinase (PMKase) (hPMK) (EC 2.7.4.2)

Protein sequence:

1_MAPLG 6_ GAPRL 11_ VLLFS 16_ GKRKS 21_ GKDFV 26_ TEALQ 31_ SRLGA 36_ DVCAV 41_ LRLSG 46_ PLKEQ 51_ YAQEH 56_ GLNFQ 61_ RLLDT 66_ STYKE 71_ AFRKD 76_ MIRWG 81_ EEKRQ 86_ ADPGF 91_ FCRKI 96_ VEGIS 101_ QPIWL 106_ VSDTR 111_ RVSDI 116_ QWFRE 121_ AYGAV 126_ TQTVR 131_ VVALE 136_ QSRQQ 141_ RGWVF 146_ TPGVD 151_ DAESE 156_ CGLDN 161_ FGDFD 166_ WVIEN 171_ HGVEQ 176_ RLEEQ 181_ LENLI 186_EFIRS

Protein annotations

Protein functions:

1: Catalyzes the reversible ATP-dependent phosphorylation of mevalonate 5-phosphate to produce mevalonate diphosphate and ADP, a key step in the mevalonic acid mediated biosynthesis of isopentenyl diphosphate and other polyisoprenoid metabolites