Gene name: PON2

Uniprot entry:

Q15165

Protein names:

Serum paraoxonase/arylesterase 2 (PON 2) (EC 3.1.1.2) (EC 3.1.1.81) (Aromatic esterase 2) (A-esterase 2) (Serum aryldialkylphosphatase 2)

Protein sequence:

1_MGRLV 6_ AVGLL 11_ GIALA 16_ LLGER 21_ LLALR 26_ NRLKA 31_ SREVE 36_ SVDLP 41_ HCHLI 46_ KGIEA 51_ GSEDI 56_ DILPN 61_ GLAFF 66_ SVGLK 71_ FPGLH 76_ SFAPD 81_ KPGGI 86_ LMMDL 91_ KEEKP 96_ RAREL 101_ RISRG 106_ FDLAS 111_ FNPHG 116_ ISTFI 121_ DNDDT 126_ VYLFV 131_ VNHPE 136_ FKNTV 141_ EIFKF 146_ EEAEN 151_ SLLHL 156_ KTVKH 161_ ELLPS 166_ VNDIT 171_ AVGPA 176_ HFYAT 181_ NDHYF 186_ SDPFL 191_ KYLET 196_ YLNLH 201_ WANVV 206_ YYSPN 211_ EVKVV 216_ AEGFD 221_ SANGI 226_ NISPD 231_ DKYIY 236_ VADIL 241_ AHEIH 246_ VLEKH 251_ TNMNL 256_ TQLKV 261_ LELDT 266_ LVDNL 271_ SIDPS 276_ SGDIW 281_ VGCHP 286_ NGQKL 291_ FVYDP 296_ NNPPS 301_ SEVLR 306_ IQNIL 311_ SEKPT 316_ VTTVY 321_ ANNGS 326_ VLQGS 331_ SVASV 336_ YDGKL 341_ LIGTL 346_YHRAL

Protein annotations

Protein functions:

1: Capable of hydrolyzing lactones and a number of aromatic carboxylic acid esters. Has antioxidant activity. Is not associated with high density lipoprotein. Prevents LDL lipid peroxidation, reverses the oxidation of mildly oxidized LDL, and inhibits the ability of MM-LDL to induce monocyte chemotaxis