Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform (PP2A B subunit isoform B'-beta) (PP2A B subunit isoform B56-beta) (PP2A B subunit isoform PR61-beta) (PP2A B subunit isoform R5-beta)
1_METKL 6_ PPAST 11_ PTSPS 16_ SPGLS 21_ PVPPP 26_ DKVDG 31_ FSRRS 36_ LRRAR 41_ PRRSH 46_ SSSQF 51_ RYQSN 56_ QQELT 61_ PLPLL 66_ KDVPA 71_ SELHE 76_ LLSRK 81_ LAQCG 86_ VMFDF 91_ LDCVA 96_ DLKGK 101_ EVKRA 106_ ALNEL 111_ VECVG 116_ STRGV 121_ LIEPV 126_ YPDII 131_ RMISV 136_ NIFRT 141_ LPPSE 146_ NPEFD 151_ PEEDE 156_ PNLEP 161_ SWPHL 166_ QLVYE 171_ FFLRF 176_ LESPD 181_ FQPSV 186_ AKRYV 191_ DQKFV 196_ LMLLE 201_ LFDSE 206_ DPRER 211_ EYLKT 216_ ILHRV 221_ YGKFL 226_ GLRAY 231_ IRKQC 236_ NHIFL 241_ RFIYE 246_ FEHFN 251_ GVAEL 256_ LEILG 261_ SIING 266_ FALPL 271_ KTEHK 276_ QFLVR 281_ VLIPL 286_ HSVKS 291_ LSVFH 296_ AQLAY 301_ CVVQF 306_ LEKDA 311_ TLTEH 316_ VIRGL 321_ LKYWP 326_ KTCTQ 331_ KEVMF 336_ LGEME 341_ EILDV 346_ IEPSQ 351_ FVKIQ 356_ EPLFK 361_ QVARC 366_ VSSPH 371_ FQVAE 376_ RALYF 381_ WNNEY 386_ ILSLI 391_ EDNCH 396_ TVLPA 401_ VFGTL 406_ YQVSK 411_ EHWNQ 416_ TIVSL 421_ IYNVL 426_ KTFME 431_ MNGKL 436_ FDELT 441_ ASYKL 446_ EKQQE 451_ QQKAQ 456_ ERQEL 461_ WQGLE 466_ ELRLR 471_ RLQGT 476_ QGAKE 481_ APLQR 486_ LTPQV 491_AASGG
1: As the regulatory component of the serine/threonine-protein phosphatase 2A (PP2A) holoenzyme, modulates substrate specificity, subcellular localization, and responsiveness to phosphorylation. The phosphorylated form mediates the interaction between PP2A and AKT1, leading to AKT1 dephosphorylation