POU domain, class 4, transcription factor 3 (Brain-specific homeobox/POU domain protein 3C) (Brain-3C) (Brn-3C)
1_MMAMN 6_ SKQPF 11_ GMHPV 16_ LQEPK 21_ FSSLH 26_ SGSEA 31_ MRRVC 36_ LPAPQ 41_ LQGNI 46_ FGSFD 51_ ESLLA 56_ RAEAL 61_ AAVDI 66_ VSHGK 71_ NHPFK 76_ PDATY 81_ HTMSS 86_ VPCTS 91_ TSSTV 96_ PISHP 101_ AALTS 106_ HPHHA 111_ VHQGL 116_ EGDLL 121_ EHISP 126_ TLSVS 131_ GLGAP 136_ EHSVM 141_ PAQIH 146_ PHHLG 151_ AMGHL 156_ HQAMG 161_ MSHPH 166_ TVAPH 171_ SAMPA 176_ CLSDV 181_ ESDPR 186_ ELEAF 191_ AERFK 196_ QRRIK 201_ LGVTQ 206_ ADVGA 211_ ALANL 216_ KIPGV 221_ GSLSQ 226_ STICR 231_ FESLT 236_ LSHNN 241_ MIALK 246_ PVLQA 251_ WLEEA 256_ EAAYR 261_ EKNSK 266_ PELFN 271_ GSERK 276_ RKRTS 281_ IAAPE 286_ KRSLE 291_ AYFAI 296_ QPRPS 301_ SEKIA 306_ AIAEK 311_ LDLKK 316_ NVVRV 321_ WFCNQ 326_ RQKQK 331_RMKYS
1: Acts as a transcriptional activator (PubMed:18228599). Acts by binding to sequences related to the consensus octamer motif 5'-ATGCAAAT-3' in the regulatory regions of its target genes (PubMed:18228599). Involved in the auditory system development, required for terminal differentiation of hair cells in the inner ear (By similarity)