Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible gene C-193 protein) (Cytokine-inducible nuclear protein)
1_MMVLK 6_ VEELV 11_ TGKKN 16_ GNGEA 21_ GEFLP 26_ EDFRD 31_ GEYEA 36_ AVTLE 41_ KQEDL 46_ KTLLA 51_ HPVTL 56_ GEQQW 61_ KSEKQ 66_ REAEL 71_ KKKKL 76_ EQRSK 81_ LENLE 86_ DLEII 91_ IQLKK 96_ RKKYR 101_ KTKVP 106_ VVKEP 111_ EPEII 116_ TEPVD 121_ VPTFL 126_ KAALE 131_ NKLPV 136_ VEKFL 141_ SDKNN 146_ PDVCD 151_ EYKRT 156_ ALHRA 161_ CLEGH 166_ LAIVE 171_ KLMEA 176_ GAQIE 181_ FRDML 186_ ESTAI 191_ HWASR 196_ GGNLD 201_ VLKLL 206_ LNKGA 211_ KISAR 216_ DKLLS 221_ TALHV 226_ AVRTG 231_ HYECA 236_ EHLIA 241_ CEADL 246_ NAKDR 251_ EGDTP 256_ LHDAV 261_ RLNRY 266_ KMIRL 271_ LIMYG 276_ ADLNI 281_ KNCAG 286_ KTPMD 291_ LVLHW 296_ QNGTK 301_ AIFDS 306_ LRENS 311_YKTSR
1: May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells