Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (p90RSK2) (MAP kinase-activated protein kinase 1c) (MAPK-activated protein kinase 1c) (MAPKAP kinase 1c) (MAPKAPK-1c) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3)
1_MDLSM 6_ KKFAV 11_ RRFFS 16_ VYLRR 21_ KSRSK 26_ SSSLS 31_ RLEEE 36_ GVVKE 41_ IDISH 46_ HVKEG 51_ FEKAD 56_ PSQFE 61_ LLKVL 66_ GQGSY 71_ GKVFL 76_ VRKVK 81_ GSDAG 86_ QLYAM 91_ KVLKK 96_ ATLKV 101_ RDRVR 106_ SKMER 111_ DILAE 116_ VNHPF 121_ IVKLH 126_ YAFQT 131_ EGKLY 136_ LILDF 141_ LRGGD 146_ LFTRL 151_ SKEVM 156_ FTEED 161_ VKFYL 166_ AELAL 171_ ALDHL 176_ HSLGI 181_ IYRDL 186_ KPENI 191_ LLDEE 196_ GHIKI 201_ TDFGL 206_ SKEAI 211_ DHDKR 216_ AYSFC 221_ GTIEY 226_ MAPEV 231_ VNRRG 236_ HTQSA 241_ DWWSF 246_ GVLMF 251_ EMLTG 256_ SLPFQ 261_ GKDRK 266_ ETMAL 271_ ILKAK 276_ LGMPQ 281_ FLSGE 286_ AQSLL 291_ RALFK 296_ RNPCN 301_ RLGAG 306_ IDGVE 311_ EIKRH 316_ PFFVT 321_ IDWNT 326_ LYRKE 331_ IKPPF 336_ KPAVG 341_ RPEDT 346_ FHFDP 351_ EFTAR 356_ TPTDS 361_ PGVPP 366_ SANAH 371_ HLFRG 376_ FSFVA 381_ SSLIQ 386_ EPSQQ 391_ DLHKV 396_ PVHPI 401_ VQQLH 406_ GNNIH 411_ FTDGY 416_ EIKED 421_ IGVGS 426_ YSVCK 431_ RCVHK 436_ ATDTE 441_ YAVKI 446_ IDKSK 451_ RDPSE 456_ EIEIL 461_ LRYGQ 466_ HPNII 471_ TLKDV 476_ YDDGK 481_ FVYLV 486_ MELMR 491_ GGELL 496_ DRILR 501_ QRYFS 506_ EREAS 511_ DVLCT 516_ ITKTM 521_ DYLHS 526_ QGVVH 531_ RDLKP 536_ SNILY 541_ RDESG 546_ SPESI 551_ RVCDF 556_ GFAKQ 561_ LRAGN 566_ GLLMT 571_ PCYTA 576_ NFVAP 581_ EVLKR 586_ QGYDA 591_ ACDIW 596_ SLGIL 601_ LYTML 606_ AGFTP 611_ FANGP 616_ DDTPE 621_ EILAR 626_ IGSGK 631_ YALSG 636_ GNWDS 641_ ISDAA 646_ KDVVS 651_ KMLHV 656_ DPHQR 661_ LTAMQ 666_ VLKHP 671_ WVVNR 676_ EYLSP 681_ NQLSR 686_ QDVHL 691_ VKGAM 696_ AATYF 701_ ALNRT 706_ PQAPR 711_ LEPVL 716_ SSNLA 721_ QRRGM 726_KRLTS
1: Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of transcription factors, regulates translation, and mediates cellular proliferation, survival, and differentiation. May function as tumor suppressor in epithelial ovarian cancer cells