Nuclear receptor subfamily 6 group A member 1 (Germ cell nuclear factor) (GCNF) (hGCNF) (Retinoid receptor-related testis-specific receptor) (RTR) (hRTR)
1_MERDE 6_ PPPSG 11_ GGGGG 16_ GSAGF 21_ LEPPA 26_ ALPPP 31_ PRNGF 36_ CQDEL 41_ AELDP 46_ GTISV 51_ SDDRA 56_ EQRTC 61_ LICGD 66_ RATGL 71_ HYGII 76_ SCEGC 81_ KGFFK 86_ RSICN 91_ KRVYR 96_ CSRDK 101_ NCVMS 106_ RKQRN 111_ RCQYC 116_ RLLKC 121_ LQMGM 126_ NRKAI 131_ REDGM 136_ PGGRN 141_ KSIGP 146_ VQISE 151_ EEIER 156_ IMSGQ 161_ EFEEE 166_ ANHWS 171_ NHGDS 176_ DHSSP 181_ GNRAS 186_ ESNQP 191_ SPGST 196_ LSSSR 201_ SVELN 206_ GFMAF 211_ REQYM 216_ GMSVP 221_ PHYQY 226_ IPHLF 231_ SYSGH 236_ SPLLP 241_ QQARS 246_ LDPQS 251_ YSLIH 256_ QLLSA 261_ EDLEP 266_ LGTPM 271_ LIEDG 276_ YAVTQ 281_ AELFA 286_ LLCRL 291_ ADELL 296_ FRQIA 301_ WIKKL 306_ PFFCE 311_ LSIKD 316_ YTCLL 321_ SSTWQ 326_ ELILL 331_ SSLTV 336_ YSKQI 341_ FGELA 346_ DVTAK 351_ YSPSD 356_ EELHR 361_ FSDEG 366_ MEVIE 371_ RLIYL 376_ YHKFH 381_ QLKVS 386_ NEEYA 391_ CMKAI 396_ NFLNQ 401_ DIRGL 406_ TSASQ 411_ LEQLN 416_ KRYWY 421_ ICQDF 426_ TEYKY 431_ THQPN 436_ RFPDL 441_ MMCLP 446_ EIRYI 451_ AGKMV 456_ NVPLE 461_ QLPLL 466_ FKVVL 471_HSCKT
1: Orphan nuclear receptor that binds to a response element containing the sequence 5'-TCAAGGTCA-3' (PubMed:26769970). Acts as a regulator of embryonic stem cell pluripotency by mediating repression of POU5F1/OCT4: binds to the DR0 element within the POU5F1/OCT4 promoter and inhibits POU5F1/OCT4 expression during embryonic stem cell differentiation (PubMed:26769970). Involved in the regulation of gene expression in germ cell development during gametogenesis (By similarity)