Scaffold attachment factor B1 (SAF-B) (SAF-B1) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE-TATA-binding protein)
1_MAETL 6_ SGLGD 11_ SGAAG 16_ AAALS 21_ SASSE 26_ TGTRR 31_ LSDLR 36_ VIDLR 41_ AELRK 46_ RNVDS 51_ SGNKS 56_ VLMER 61_ LKKAI 66_ EDEGG 71_ NPDEI 76_ EITSE 81_ GNKKT 86_ SKRSS 91_ KGRKP 96_ EEEGV 101_ EDNGL 106_ EENSG 111_ DGQED 116_ VETSL 121_ ENLQD 126_ IDIMD 131_ ISVLD 136_ EAEID 141_ NGSVA 146_ DCVED 151_ DDADN 156_ LQESL 161_ SDSRE 166_ LVEGE 171_ MKELP 176_ EQLQE 181_ HAIED 186_ KETIN 191_ NLDTS 196_ SSDFT 201_ ILQEI 206_ EEPSL 211_ EPENE 216_ KILDI 221_ LGETC 226_ KSEPV 231_ KEESS 236_ ELEQP 241_ FAQDT 246_ SSVGP 251_ DRKLA 256_ EEEDL 261_ FDSAH 266_ PEEGD 271_ LDLAS 276_ ESTAH 281_ AQSSK 286_ ADSLL 291_ AVVKR 296_ EPAEQ 301_ PGDGE 306_ RTDCE 311_ PVGLE 316_ PAVEQ 321_ SSAAS 326_ ELAEA 331_ SSEEL 336_ AEAPT 341_ EAPSP 346_ EARDS 351_ KEDGR 356_ KFDFD 361_ ACNEV 366_ PPAPK 371_ ESSTS 376_ EGADQ 381_ KMSSP 386_ EDDSD 391_ TKRLS 396_ KEEKG 401_ RSSCG 406_ RNFWV 411_ SGLSS 416_ TTRAT 421_ DLKNL 426_ FSKYG 431_ KVVGA 436_ KVVTN 441_ ARSPG 446_ ARCYG 451_ FVTMS 456_ TAEEA 461_ TKCIN 466_ HLHKT 471_ ELHGK 476_ MISVE 481_ KAKNE 486_ PVGKK 491_ TSDKR 496_ DSDGK 501_ KEKSS 506_ NSDRS 511_ TNLKR 516_ DDKCD 521_ RKDDA 526_ KKGDD 531_ GSGEK 536_ SKDQD 541_ DQKPG 546_ PSERS 551_ RATKS 556_ GSRGT 561_ ERTVV 566_ MDKSK 571_ GVPVI 576_ SVKTS 581_ GSKER 586_ ASKSQ 591_ DRKSA 596_ SREKR 601_ SVVSF 606_ DKVKE 611_ PRKSR 616_ DSESH 621_ SRVRE 626_ RSERE 631_ QRMQA 636_ QWERE 641_ ERERL 646_ EIARE 651_ RLAFQ 656_ RQRLE 661_ RERME 666_ RERLE 671_ RERMH 676_ VEHER 681_ RREQE 686_ RIHRE 691_ REELR 696_ RQQEL 701_ RYEQE 706_ RRPAV 711_ RRPYD 716_ LDRRD 721_ DAYWP 726_ EAKRA 731_ ALDER 736_ YHSDF 741_ NRQDR 746_ FHDFD 751_ HRDRG 756_ RYPDH 761_ SVDRR 766_ EGSRS 771_ MMGER 776_ EGQHY 781_ PERHG 786_ GPERH 791_ GRDSR 796_ DGWGG 801_ YGSDK 806_ RMSEG 811_ RGLPP 816_ PPRRD 821_ WGDHG 826_ RREDD 831_ RSWQG 836_ TADGG 841_ MMDRD 846_ HKRWQ 851_ GGERS 856_ MSGHS 861_ GPGHM 866_ MNRGG 871_ MSGRG 876_ SFAPG 881_ GASRG 886_ HPIPH 891_ GGMQG 896_ GFGGQ 901_ SRGSR 906_PSDAR
1: Binds to scaffold/matrix attachment region (S/MAR) DNA and forms a molecular assembly point to allow the formation of a 'transcriptosomal' complex (consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing (PubMed:9671816). Functions as an estrogen receptor corepressor and can also bind to the HSP27 promoter and decrease its transcription (PubMed:12660241). Thereby acts as a negative regulator of cell proliferation (PubMed:12660241). When associated with RBMX, binds to and stimulates transcription from the SREBF1 promoter (By similarity)