Gene name: SS18

Uniprot entry:

Q15532

Protein names:

Protein SSXT (Protein SYT) (Synovial sarcoma translocated to X chromosome protein)

Protein sequence:

1_MSVAF 6_ AAPRQ 11_ RGKGE 16_ ITPAA 21_ IQKML 26_ DDNNH 31_ LIQCI 36_ MDSQN 41_ KGKTS 46_ ECSQY 51_ QQMLH 56_ TNLVY 61_ LATIA 66_ DSNQN 71_ MQSLL 76_ PAPPT 81_ QNMPM 86_ GPGGM 91_ NQSGP 96_ PPPPR 101_ SHNMP 106_ SDGMV 111_ GGGPP 116_ APHMQ 121_ NQMNG 126_ QMPGP 131_ NHMPM 136_ QGPGP 141_ NQLNM 146_ TNSSM 151_ NMPSS 156_ SHGSM 161_ GGYNH 166_ SVPSS 171_ QSMPV 176_ QNQMT 181_ MSQGQ 186_ PMGNY 191_ GPRPN 196_ MSMQP 201_ NQGPM 206_ MHQQP 211_ PSQQY 216_ NMPQG 221_ GGQHY 226_ QGQQP 231_ PMGMM 236_ GQVNQ 241_ GNHMM 246_ GQRQI 251_ PPYRP 256_ PQQGP 261_ PQQYS 266_ GQEDY 271_ YGDQY 276_ SHGGQ 281_ GPPEG 286_ MNQQY 291_ YPDGH 296_ NDYGY 301_ QQPSY 306_ PEQGY 311_ DRPYE 316_ DSSQH 321_ YYEGG 326_ NSQYG 331_ QQQDA 336_ YQGPP 341_ PQQGY 346_ PPQQQ 351_ QYPGQ 356_ QGYPG 361_ QQQGY 366_ GPSQG 371_ GPGPQ 376_ YPNYP 381_ QGQGQ 386_ QYGGY 391_ RPTQP 396_ GPPQP 401_ PQQRP 406_ YGYDQ 411_GQYGN

Protein annotations

Protein functions:

1: Appears to function synergistically with RBM14 as a transcriptional coactivator. Isoform 1 and isoform 2 function in nuclear receptor coactivation. Isoform 1 and isoform 2 function in general transcriptional coactivation. Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner (PubMed:29374058)