Gene name: TAF7

Uniprot entry:

Q15545

Protein names:

Transcription initiation factor TFIID subunit 7 (RNA polymerase II TBP-associated factor subunit F) (Transcription initiation factor TFIID 55 kDa subunit) (TAF(II)55) (TAFII-55) (TAFII55)

Protein sequence:

1_MSKSK 6_ DDAPH 11_ ELESQ 16_ FILRL 21_ PPEYA 26_ STVRR 31_ AVQSG 36_ HVNLK 41_ DRLTI 46_ ELHPD 51_ GRHGI 56_ VRVDR 61_ VPLAS 66_ KLVDL 71_ PCVME 76_ SLKTI 81_ DKKTF 86_ YKTAD 91_ ICQML 96_ VSTVD 101_ GDLYP 106_ PVEEP 111_ VASTD 116_ PKASK 121_ KKDKD 126_ KEKKF 131_ IWNHG 136_ ITLPL 141_ KNVRK 146_ RRFRK 151_ TAKKK 156_ YIESP 161_ DVEKE 166_ VKRLL 171_ STDAE 176_ AVSTR 181_ WEIIA 186_ EDETK 191_ EAENQ 196_ GLDIS 201_ SPGMS 206_ GHRQG 211_ HDSLE 216_ HDELR 221_ EIFND 226_ LSSSS 231_ EDEDE 236_ TQHQD 241_ EEDIN 246_ IIDTE 251_ EDLER 256_ QLQDK 261_ LNESD 266_ EQHQE 271_ NEGTN 276_ QLVMG 281_ IQKQI 286_ DNMKG 291_ KLQET 296_ QDRAK 301_ RQEDL 306_ IMKVE 311_ NLALK 316_ NRFQA 321_ VLDEL 326_ KQKED 331_ REKEQ 336_ LSSLQ 341_EELES

Protein annotations

Protein functions:

1: The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription (PubMed:33795473). TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC) (PubMed:33795473). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13 (PubMed:10438527, PubMed:33795473). TAF7 forms a promoter DNA binding subcomplex of TFIID, together with TAF1 and TAF2 (PubMed:33795473). Part of a TFIID complex containing TAF10 (TFIID alpha) and a TFIID complex lacking TAF10 (TFIID beta) (PubMed:10438527)