Transcription elongation factor A protein 2 (Testis-specific S-II) (Transcription elongation factor S-II protein 2) (Transcription elongation factor TFIIS.l)
1_MMGKE 6_ EEIAR 11_ IARRL 16_ DKMVT 21_ KKSAE 26_ GAMDL 31_ LRELK 36_ AMPIT 41_ LHLLQ 46_ STRVG 51_ MSVNA 56_ LRKQS 61_ SDEEV 66_ IALAK 71_ SLIKS 76_ WKKLL 81_ DASDA 86_ KARER 91_ GRGMP 96_ LPTSS 101_ RDASE 106_ APDPS 111_ RKRPE 116_ LPRAP 121_ STPRI 126_ TTFPP 131_ VPVTC 136_ DAVRN 141_ KCREM 146_ LTAAL 151_ QTDHD 156_ HVAIG 161_ ADCER 166_ LSAQI 171_ EECIF 176_ RDVGN 181_ TDMKY 186_ KNRVR 191_ SRISN 196_ LKDAK 201_ NPDLR 206_ RNVLC 211_ GAITP 216_ QQIAV 221_ MTSEE 226_ MASDE 231_ LKEIR 236_ KAMTK 241_ EAIRE 246_ HQMAR 251_ TGGTQ 256_ TDLFT 261_ CGKCR 266_ KKNCT 271_ YTQVQ 276_ TRSSD 281_ EPMTT 286_ FVVCN 291_ECGNR
1: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus