TATA box-binding protein-associated factor RNA polymerase I subunit A (RNA polymerase I-specific TBP-associated factor 48 kDa) (TAFI48) (TATA box-binding protein-associated factor 1A) (TBP-associated factor 1A) (Transcription factor SL1) (Transcription initiation factor SL1/TIF-IB subunit A)
1_MSDFS 6_ EELKG 11_ PVTDD 16_ EEVET 21_ SVLSG 26_ AGMHF 31_ PWLQT 36_ YVETV 41_ AIGGK 46_ RRKDF 51_ AQTTS 56_ ACLSF 61_ IQEAL 66_ LKHQW 71_ QQAAE 76_ YMYSY 81_ FQTLE 86_ DSDSY 91_ KRQAA 96_ PEIIW 101_ KLGSE 106_ ILFYH 111_ PKSNM 116_ ESFNT 121_ FANRM 126_ KNIGV 131_ MNYLK 136_ ISLQH 141_ ALYLL 146_ HHGML 151_ KDAKR 156_ NLSEA 161_ ETWRH 166_ GENTS 171_ SREIL 176_ INLIQ 181_ AYKGL 186_ LQYYT 191_ WSEKK 196_ MELSK 201_ LDKDD 206_ YAYNA 211_ VAQDV 216_ FNHSW 221_ KTSAN 226_ ISALI 231_ KIPGV 236_ WDPFV 241_ KSYVE 246_ MLEFY 251_ GDRDG 256_ AQEVL 261_ TNYAY 266_ DEKFP 271_ SNPNA 276_ HIYLY 281_ NFLKR 286_ QKAPR 291_ SKLIS 296_ VLKIL 301_ YQIVP 306_ SHKLM 311_ LEFHT 316_ LLRKS 321_ EKEEH 326_ RKLGL 331_ EVLFG 336_ VLDFA 341_ GCTKN 346_ ITAWK 351_ YLAKY 356_ LKNIL 361_ MGNHL 366_ AWVQE 371_ EWNSR 376_ KNWWP 381_ GFHFS 386_ YFWAK 391_ SDWKE 396_ DTALA 401_ CEKAF 406_ VAGLL 411_ LGKGC 416_ RYFRY 421_ ILKQD 426_ HQILG 431_ KKIKR 436_ MKRSV 441_KKYSI
1: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits