Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (NHE3 kinase A regulatory protein E3KARP) (SRY-interacting protein 1) (SIP-1) (Sodium-hydrogen exchanger regulatory factor 2) (Solute carrier family 9 isoform A3 regulatory factor 2) (Tyrosine kinase activator protein 1) (TKA-1)
1_MAAPE 6_ PLRPR 11_ LCRLV 16_ RGEQG 21_ YGFHL 26_ HGEKG 31_ RRGQF 36_ IRRVE 41_ PGSPA 46_ EAAAL 51_ RAGDR 56_ LVEVN 61_ GVNVE 66_ GETHH 71_ QVVQR 76_ IKAVE 81_ GQTRL 86_ LVVDQ 91_ ETDEE 96_ LRRRQ 101_ LTCTE 106_ EMAQR 111_ GLPPA 116_ HDPWE 121_ PKPDW 126_ AHTGS 131_ HSSEA 136_ GKKDV 141_ SGPLR 146_ ELRPR 151_ LCHLR 156_ KGPQG 161_ YGFNL 166_ HSDKS 171_ RPGQY 176_ IRSVD 181_ PGSPA 186_ ARSGL 191_ RAQDR 196_ LIEVN 201_ GQNVE 206_ GLRHA 211_ EVVAS 216_ IKARE 221_ DEARL 226_ LVVDP 231_ ETDEH 236_ FKRLR 241_ VTPTE 246_ EHVEG 251_ PLPSP 256_ VTNGT 261_ SPAQL 266_ NGGSA 271_ CSSRS 276_ DLPGS 281_ DKDTE 286_ DGSAW 291_ KQDPF 296_ QESGL 301_ HLSPT 306_ AAEAK 311_ EKARA 316_ MRVNK 321_ RAPQM 326_ DWNRK 331_REIFS
1: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3 (PubMed:18829453). May also act as scaffold protein in the nucleus