Cdc42-interacting protein 4 (Protein Felic) (Salt tolerant protein) (hSTP) (Thyroid receptor-interacting protein 10) (TR-interacting protein 10) (TRIP-10)
1_MDWGT 6_ ELWDQ 11_ FEVLE 16_ RHTQW 21_ GLDLL 26_ DRYVK 31_ FVKER 36_ TEVEQ 41_ AYAKQ 46_ LRSLV 51_ KKYLP 56_ KRPAK 61_ DDPES 66_ KFSQQ 71_ QSFVQ 76_ ILQEV 81_ NDFAG 86_ QRELV 91_ AENLS 96_ VRVCL 101_ ELTKY 106_ SQEMK 111_ QERKM 116_ HFQEG 121_ RRAQQ 126_ QLENG 131_ FKQLE 136_ NSKRK 141_ FERDC 146_ REAEK 151_ AAQTA 156_ ERLDQ 161_ DINAT 166_ KADVE 171_ KAKQQ 176_ AHLRS 181_ HMAEE 186_ SKNEY 191_ AAQLQ 196_ RFNRD 201_ QAHFY 206_ FSQMP 211_ QIFDK 216_ LQDMD 221_ ERRAT 226_ RLGAG 231_ YGLLS 236_ EAELE 241_ VVPII 246_ AKCLE 251_ GMKVA 256_ ANAVD 261_ PKNDS 266_ HVLIE 271_ LHKSG 276_ FARPG 281_ DVEFE 286_ DFSQP 291_ MNRAP 296_ SDSSL 301_ GTPSD 306_ GRPEL 311_ RGPGR 316_ SRTKR 321_ WPFGK 326_ KNKPR 331_ PPPLS 336_ PLGGP 341_ VPSAL 346_ PNGPP 351_ SPRSG 356_ RDPLA 361_ ILSEI 366_ SKSVK 371_ PRLAS 376_ FRSLR 381_ GSRGT 386_ VVTED 391_ FSHLP 396_ PEQQR 401_ KRLQQ 406_ QLEER 411_ SRELQ 416_ KEVDQ 421_ REALK 426_ KMKDV 431_ YEKTP 436_ QMGDP 441_ ASLEP 446_ QIAET 451_ LSNIE 456_ RLKLE 461_ VQKYE 466_ AWLAE 471_ AESRV 476_ LSNRG 481_ DSLSR 486_ HARPP 491_ DPPAS 496_ APPDS 501_ SSNSA 506_ SQDTK 511_ ESSEE 516_ PPSEE 521_ SQDTP 526_ IYTEF 531_ DEDFE 536_ EEPTS 541_ PIGHC 546_ VAIYH 551_ FEGSS 556_ EGTIS 561_ MAEGE 566_ DLSLM 571_ EEDKG 576_ DGWTR 581_ VRRKE 586_ GGEGY 591_ VPTSY 596_LRVTL
1: Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL