Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TR-interacting protein 8) (TRIP-8)
1_MAVET 6_ RAELV 11_ GKRFL 16_ CVAVG 21_ DEARS 26_ ERWES 31_ GRGWR 36_ SWRAG 41_ VIRAV 46_ SHRDS 51_ RNPDL 56_ AVYVE 61_ FDDLE 66_ WDKRE 71_ WVKVY 76_ EDFST 81_ FLVEY 86_ HLIWA 91_ KRNDP 96_ SQTQG 101_ SKSKQ 106_ IQWPA 111_ LTFKP 116_ LVERN 121_ IPSSV 126_ TAVEF 131_ LVDKQ 136_ LDFLT 141_ EDSAF 146_ QPYQD 151_ DIDSL 156_ NPVLR 161_ DNPQL 166_ HEEVK 171_ VWVKE 176_ QKVQE 181_ IFMQG 186_ PYSLN 191_ GYRVR 196_ VYRQD 201_ SATQW 206_ FTGII 211_ THHDL 216_ FTRTM 221_ IVMND 226_ QVLEP 231_ QNVDP 236_ SMVQM 241_ TFLDD 246_ VVHSL 251_ LKGEN 256_ IGITS 261_ RRRSR 266_ ANQNV 271_ NAVHS 276_ HYTRA 281_ QANSP 286_ RPAMN 291_ SQAAV 296_ PKQNT 301_ HQQQQ 306_ QRSIR 311_ PNKRK 316_ GSDSS 321_ IPDEE 326_ KMKEE 331_ KYDYI 336_ SRGEN 341_ PKGKN 346_ KHLMN 351_ KRRKP 356_ EEDEK 361_ KLNMK 366_ RLRTD 371_ NVSDF 376_ SESSD 381_ SENSN 386_ KRIID 391_ NSSEQ 396_ KPENE 401_ LKNKN 406_ TSKIN 411_ GEEGK 416_ PHNNE 421_ KAGEE 426_ TLKNS 431_ QPPWD 436_ QIQED 441_ KKHEE 446_ AEKRK 451_ SVDTQ 456_ LQEDM 461_ IIHSS 466_ EQSTV 471_ SDHNS 476_ NDLLP 481_ QECNM 486_ DKTHT 491_ MELLP 496_ KEKFV 501_ SRPPT 506_ PKCVI 511_ DITND 516_ TNLEK 521_ VAQEN 526_ SSTFG 531_ LQTLQ 536_ KMDPN 541_ VSDSK 546_ HSIAN 551_ AKFLE 556_ TAKKD 561_ SDQSW 566_ VSDVV 571_ KVDLT 576_ QSSVT 581_ NASSG 586_ NDHLN 591_ MEKEK 596_ YVSYI 601_ SPLSA 606_ VSVME 611_ DKLHK 616_ RSPPP 621_ ETIKS 626_ KLNTS 631_ VDTHK 636_ IKSSP 641_ SPEVV 646_ KPKIT 651_ HSPDS 656_ VKSKA 661_ TYVNS 666_ QATGE 671_ RRLAN 676_ KIEHE 681_ LSRCS 686_ FHPIP 691_ TRSST 696_ LETTK 701_ SPLII 706_ DKNEH 711_ FTVYR 716_ DPALI 721_ GSETG 726_ ANHIS 731_ PFLSQ 736_ HPFPL 741_ HSSSH 746_ RTCLN 751_ PGTHH 756_ PALTP 761_ APHLL 766_ AGSSS 771_ QTPLP 776_ TINTH 781_ PLTSG 786_ PHHAV 791_ HHPHL 796_ LPTVL 801_ PGVPT 806_ ASLLG 811_ GHPRL 816_ ESAHA 821_ SSLSH 826_ LALAH 831_ QQQQQ 836_ LLQHQ 841_ SPHLL 846_ GQAHP 851_ SASYN 856_ QLGLY 861_ PIIWQ 866_ YPNGT 871_ HAYSG 876_ LGLPS 881_ SKWVH 886_ PENAV 891_ NAEAS 896_ LRRNS 901_ PSPWL 906_ HQPTP 911_ VTSAD 916_ GIGLL 921_ SHIPV 926_ RPSSA 931_ EPHRP 936_ LKITA 941_ HSSPP 946_ LTKTL 951_ VDHHK 956_ EELER 961_ KAFME 966_ PLRSV 971_ ASTSA 976_ KNDLD 981_ LNRSQ 986_ TGKDC 991_ HLHRH 996_ FVDPV 1001_ LNQLQ 1006_ RPPQE 1011_ TGERL 1016_ NKYKE 1021_ EHRRI 1026_ LQESI 1031_ DVAPF 1036_ TTKIK 1041_ GLEGE 1046_ RENYS 1051_ RVASS 1056_ SSSPK 1061_ SHIIK 1066_ QDMDV 1071_ ERSVS 1076_ DLYKM 1081_ KHSVP 1086_ QSLPQ 1091_ SNYFT 1096_ TLSNS 1101_ VVNEP 1106_ PRSYP 1111_ SKEVS 1116_ NIYGD 1121_ KQSNA 1126_ LAAAA 1131_ ANPQT 1136_ LTSFI 1141_ TSLSK 1146_ PPPLI 1151_ KHQPE 1156_ SEGLV 1161_ GKIPE 1166_ HLPHQ 1171_ IASHS 1176_ VTTFR 1181_ NDCRS 1186_ PTHLT 1191_ VSSTN 1196_ TLRSM 1201_ PALHR 1206_ APVFH 1211_ PPIHH 1216_ SLERK 1221_ EGSYS 1226_ SLSPP 1231_ TLTPV 1236_ MPVNA 1241_ GGKVQ 1246_ ESQKP 1251_ PTLIP 1256_ EPKDS 1261_ QANFK 1266_ SSSEQ 1271_ SLTEM 1276_ WRPNN 1281_ NLSKE 1286_ KTEWH 1291_ VEKSS 1296_ GKLQA 1301_ AMASV 1306_ IVRPS 1311_ SSTKT 1316_ DSMPA 1321_ MQLAS 1326_ KDRVS 1331_ ERSSA 1336_ GAHKT 1341_ DCLKL 1346_ AEAGE 1351_ TGRII 1356_ LPNVN 1361_ SDSVH 1366_ TKSEK 1371_ NFQAV 1376_ SQGSV 1381_ PSSVM 1386_ SAVNT 1391_ MCNTK 1396_ TDVIT 1401_ SAADT 1406_ TSVSS 1411_ WGGSE 1416_ VISSL 1421_ SNTIL 1426_ ASTSS 1431_ ECVSS 1436_ KSVSQ 1441_ PVAQK 1446_ QECKV 1451_ STTAP 1456_ VTLAS 1461_ SKTGS 1466_ VVQPS 1471_ SGFSG 1476_ TTDFI 1481_ HLKKH 1486_ KAALA 1491_ AAQYK 1496_ SSNAS 1501_ ETEPN 1506_ AIKNQ 1511_ TLSAS 1516_ LPLDS 1521_ TVICS 1526_ TINKA 1531_ NSVGN 1536_ GQASQ 1541_ TSQPN 1546_ YHTKL 1551_ KKAWL 1556_ TRHSE 1561_ EDKNT 1566_ NKMEN 1571_ SGNSV 1576_ SEIIK 1581_ PCSVN 1586_ LIAST 1591_ SSDIQ 1596_ NSVDS 1601_ KIIVD 1606_ KYVKD 1611_ DKVNR 1616_ RKAKR 1621_ TYESG 1626_ SESGD 1631_ SDESE 1636_ SKSEQ 1641_ RTKRQ 1646_ PKPTY 1651_ KKKQN 1656_ DLQKR 1661_ KGEIE 1666_ EDLKP 1671_ NGVLS 1676_ RSAKE 1681_ RSKLK 1686_ LQSNS 1691_ NTGIP 1696_ RSVLK 1701_ DWRKV 1706_ KKLKQ 1711_ TGESF 1716_ LQDDS 1721_ CCEIG 1726_ PNLQK 1731_ CRECR 1736_ LIRSK 1741_ KGEEP 1746_ AHSPV 1751_ FCRFY 1756_ YFRRL 1761_ SFSKN 1766_ GVVRI 1771_ DGFSS 1776_ PDQYD 1781_ DEAMS 1786_ LWTHE 1791_ NFEDD 1796_ ELDIE 1801_ TSKYI 1806_ LDIIG 1811_ DKFCQ 1816_ LVTSE 1821_ KTALS 1826_ WVKKD 1831_ AKIAW 1836_ KRAVR 1841_ GVREM 1846_ CDACE 1851_ ATLFN 1856_ IHWVC 1861_ QKCGF 1866_ VVCLD 1871_ CYKAK 1876_ ERKSS 1881_ RDKEL 1886_ YAWMK 1891_ CVKGQ 1896_ PHDHK 1901_ HLMPT 1906_ QIIPG 1911_ SVLTD 1916_ LLDAM 1921_ HTLRE 1926_ KYGIK 1931_ SHCHC 1936_ TNKQN 1941_ LQVGN 1946_ FPTMN 1951_ GVSQV 1956_ LQNVL 1961_ NHSNK 1966_ ISLCM 1971_ PESQQ 1976_ QNTPP 1981_ KSEKN 1986_ GGSSP 1991_ ESDVG 1996_ TDNKL 2001_ TPPES 2006_ QSPLH 2011_ WLADL 2016_ AEQKA 2021_ REEKK 2026_ ENKEL 2031_ TLENQ 2036_ IKEER 2041_ EQDNS 2046_ ESPNG 2051_ RTSPL 2056_ VSQNN 2061_ EQGST 2066_ LRDLL 2071_ TTTAG 2076_ KLRVG 2081_ STDAG 2086_ IAFAP 2091_ VYSMG 2096_ APSSK 2101_ SGRTM 2106_ PNILD 2111_ DIIAS 2116_ VVENK 2121_ IPPSK 2126_ TSKIN 2131_ VKPEL 2136_ KEEPE 2141_ ESIIS 2146_ AVDEN 2151_ NKLYS 2156_ DIPHS 2161_ WICEK 2166_ HILWL 2171_ KDYKN 2176_ SSNWK 2181_ LFKEC 2186_ WKQGQ 2191_ PAVVS 2196_ GVHKK 2201_ MNISL 2206_ WKAES 2211_ ISLDF 2216_ GDHQA 2221_ DLLNC 2226_ KDSII 2231_ SNANV 2236_ KEFWD 2241_ GFEEV 2246_ SKRQK 2251_ NKSGE 2256_ TVVLK 2261_ LKDWP 2266_ SGEDF 2271_ KTMMP 2276_ ARYED 2281_ LLKSL 2286_ PLPEY 2291_ CNPEG 2296_ KFNLA 2301_ SHLPG 2306_ FFVRP 2311_ DLGPR 2316_ LCSAY 2321_ GVVAA 2326_ KDHDI 2331_ GTTNL 2336_ HIEVS 2341_ DVVNI 2346_ LVYVG 2351_ IAKGN 2356_ GILSK 2361_ AGILK 2366_ KFEEE 2371_ DLDDI 2376_ LRKRL 2381_ KDSSE 2386_ IPGAL 2391_ WHIYA 2396_ GKDVD 2401_ KIREF 2406_ LQKIS 2411_ KEQGL 2416_ EVLPE 2421_ HDPIR 2426_ DQSWY 2431_ VNKKL 2436_ RQRLL 2441_ EEYGV 2446_ RTCTL 2451_ IQFLG 2456_ DAIVL 2461_ PAGAL 2466_ HQVQN 2471_ FHSCI 2476_ QVTED 2481_ FVSPE 2486_ HLVES 2491_ FHLTQ 2496_ ELRLL 2501_ KEEIN 2506_ YDDKL 2511_ QVKNI 2516_ LYHAV 2521_ KEMVR 2526_ ALKIH 2531_EDEVE
1: Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes (By similarity)