Probable G-protein coupled receptor 19 (GPR-NGA)
1_MVFAH 6_ RMDNS 11_ KPHLI 16_ IPTLL 21_ VPLQN 26_ RSCTE 31_ TATPL 36_ PSQYL 41_ MELSE 46_ EHSWM 51_ SNQTD 56_ LHYVL 61_ KPGEV 66_ ATASI 71_ FFGIL 76_ WLFSI 81_ FGNSL 86_ VCLVI 91_ HRSRR 96_ TQSTT 101_ NYFVV 106_ SMACA 111_ DLLIS 116_ VASTP 121_ FVLLQ 126_ FTTGR 131_ WTLGS 136_ ATCKV 141_ VRYFQ 146_ YLTPG 151_ VQIYV 156_ LLSIC 161_ IDRFY 166_ TIVYP 171_ LSFKV 176_ SREKA 181_ KKMIA 186_ ASWVF 191_ DAGFV 196_ TPVLF 201_ FYGSN 206_ WDSHC 211_ NYFLP 216_ SSWEG 221_ TAYTV 226_ IHFLV 231_ GFVIP 236_ SVLII 241_ LFYQK 246_ VIKYI 251_ WRIGT 256_ DGRTV 261_ RRTMN 266_ IVPRT 271_ KVKTI 276_ KMFLI 281_ LNLLF 286_ LLSWL 291_ PFHVA 296_ QLWHP 301_ HEQDY 306_ KKSSL 311_ VFTAI 316_ TWISF 321_ SSSAS 326_ KPTLY 331_ SIYNA 336_ NFRRG 341_ MKETF 346_ CMSSM 351_ KCYRS 356_ NAYTI 361_ TTSSR 366_ MAKKN 371_ YVGIS 376_ EIPSM 381_ AKTIT 386_ KDSIY 391_ DSFDR 396_ EAKEK 401_ KLAWP 406_INSNP
1: G-protein coupled receptor that plays a role in the regulation of circadian rhythms and energy metabolism. Participates in maintaining proper circadian gene expression in the suprachiasmatic nucleus (SCN), the locus of the master circadian clock in the brain (By similarity). May function as a coordinator of aging-associated metabolic dysfunction, stress response, DNA integrity management, and eventual senescence (PubMed:37239845). Upon binding to adropin, modulates mitochondrial energy metabolism via the p44/42-PDK4 signaling pathway, influencing pyruvate dehydrogenase activity (By similarity)