Coiled-coil domain-containing protein 85B (Hepatitis delta antigen-interacting protein A) (Delta-interacting protein A)
1_MEAEA 6_ GGLEE 11_ LTDEE 16_ MAALG 21_ KEELV 26_ RRLRR 31_ EEAAR 36_ LAALV 41_ QRGRL 46_ MQEVN 51_ RQLQG 56_ HLGEI 61_ RELKQ 66_ LNRRL 71_ QAENR 76_ ELRDL 81_ CCFLD 86_ SERQR 91_ GRRAA 96_ RQWQL 101_ FGTQA 106_ SRAVR 111_ EDLGG 116_ CWQKL 121_ AELEG 126_ RQEEL 131_ LRENL 136_ ALKEL 141_ CLALG 146_ EEWGP 151_ RGGPS 156_ GAGGS 161_ GAGPA 166_ PELAL 171_ PPCGP 176_ RDLGD 181_ GSSST 186_ GSVGS 191_ PDQLP 196_LACSP
1: Functions as a transcriptional repressor (PubMed:17014843). May inhibit the activity of CTNNB1 in a TP53-dependent manner and thus regulate cell growth (PubMed:17873903). May function in adipocyte differentiation, negatively regulating mitotic clonal expansion (By similarity). Plays a role in cell-cell adhesion and epithelium development through its interaction with proteins of the beta-catenin family (By similarity)
2: (Microbial infection) Plays a role in hepatitis delta virus (HDV) genomic replication