Septin-7 (CDC10 protein homolog)
1_MSVSA 6_ RSAAA 11_ EERSV 16_ NSSTM 21_ VAQQK 26_ NLEGY 31_ VGFAN 36_ LPNQV 41_ YRKSV 46_ KRGFE 51_ FTLMV 56_ VGESG 61_ LGKST 66_ LINSL 71_ FLTDL 76_ YSPEY 81_ PGPSH 86_ RIKKT 91_ VQVEQ 96_ SKVLI 101_ KEGGV 106_ QLLLT 111_ IVDTP 116_ GFGDA 121_ VDNSN 126_ CWQPV 131_ IDYID 136_ SKFED 141_ YLNAE 146_ SRVNR 151_ RQMPD 156_ NRVQC 161_ CLYFI 166_ APSGH 171_ GLKPL 176_ DIEFM 181_ KRLHE 186_ KVNII 191_ PLIAK 196_ ADTLT 201_ PEECQ 206_ QFKKQ 211_ IMKEI 216_ QEHKI 221_ KIYEF 226_ PETDD 231_ EEENK 236_ LVKKI 241_ KDRLP 246_ LAVVG 251_ SNTII 256_ EVNGK 261_ RVRGR 266_ QYPWG 271_ VAEVE 276_ NGEHC 281_ DFTIL 286_ RNMLI 291_ RTHMQ 296_ DLKDV 301_ TNNVH 306_ YENYR 311_ SRKLA 316_ AVTYN 321_ GVDNN 326_ KNKGQ 331_ LTKSP 336_ LAQME 341_ EERRE 346_ HVAKM 351_ KKMEM 356_ EMEQV 361_ FEMKV 366_ KEKVQ 371_ KLKDS 376_ EAELQ 381_ RRHEQ 386_ MKKNL 391_ EAQHK 396_ ELEEK 401_ RRQFE 406_ DEKAN 411_ WEAQQ 416_ RILEQ 421_ QNSSR 426_ TLEKN 431_KKKGK
1: Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (PubMed:25588830)