Gene name: TAF9

Uniprot entry:

Q16594

Protein names:

Transcription initiation factor TFIID subunit 9 (RNA polymerase II TBP-associated factor subunit G) (STAF31/32) (Transcription initiation factor TFIID 31 kDa subunit) (TAFII-31) (TAFII31) (Transcription initiation factor TFIID 32 kDa subunit) (TAFII-32) (TAFII32)

Protein sequence:

1_MESGK 6_ TASPK 11_ SMPKD 16_ AQMMA 21_ QILKD 26_ MGITE 31_ YEPRV 36_ INQML 41_ EFAFR 46_ YVTTI 51_ LDDAK 56_ IYSSH 61_ AKKAT 66_ VDADD 71_ VRLAI 76_ QCRAD 81_ QSFTS 86_ PPPRD 91_ FLLDI 96_ ARQRN 101_ QTPLP 106_ LIKPY 111_ SGPRL 116_ PPDRY 121_ CLTAP 126_ NYRLK 131_ SLQKK 136_ ASTSA 141_ GRITV 146_ PRLSV 151_ GSVTS 156_ RPSTP 161_ TLGTP 166_ TPQTM 171_ SVSTK 176_ VGTPM 181_ SLTGQ 186_ RFTVQ 191_ MPTSQ 196_ SPAVK 201_ ASIPA 206_ TSAVQ 211_ NVLIN 216_ PSLIG 221_ SKNIL 226_ ITTNM 231_ MSSQN 236_ TANES 241_ SNALK 246_ RKRED 251_ DDDDD 256_DDDDD

Protein annotations

Protein functions:

1: The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription (PubMed:33795473). TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC) (PubMed:33795473). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13 (PubMed:33795473). TAF9 is also a component of the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex (PubMed:15899866). TAF9 and its paralog TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes (PubMed:15899866). Essential for cell viability (PubMed:15899866). May have a role in gene regulation associated with apoptosis (PubMed:15899866)