POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (BOB-1) (OCA-B) (OCT-binding factor 1)
1_MLWQK 6_ PTAPE 11_ QAPAP 16_ ARPYQ 21_ GVRVK 26_ EPVKE 31_ LLRRK 36_ RGHAS 41_ SGAAP 46_ APTAV 51_ VLPHQ 56_ PLATY 61_ TTVGP 66_ SCLDM 71_ EGSVS 76_ AVTEE 81_ AALCA 86_ GWLSQ 91_ PTPAT 96_ LQPLA 101_ PWTPY 106_ TEYVP 111_ HEAVS 116_ CPYSA 121_ DMYVQ 126_ PVCPS 131_ YTVVG 136_ PSSVL 141_ TYASP 146_ PLITN 151_ VTTRS 156_ SATPA 161_ VGPPL 166_ EGPEH 171_ QAPLT 176_ YFPWP 181_ QPLST 186_ LPTST 191_ LQYQP 196_ PAPAL 201_ PGPQF 206_ VQLPI 211_ SIPEP 216_ VLQDM 221_ EDPRR 226_ AASSL 231_ TIDKL 236_ LLEEE 241_ DSDAY 246_ ALNHT 251_LSVEG
1: Transcriptional coactivator that specifically associates with either POU2F1/OCT1 or POU2F2/OCT2 (PubMed:7859290). It boosts the POU2F1/OCT1 mediated promoter activity and to a lesser extent, that of POU2F2/OCT2 (PubMed:7779176). It recognizes the POU domains of POU2F1/OCT1 and POU2F2/OCT2 (PubMed:7779176). It is essential for the response of B-cells to antigens and required for the formation of germinal centers (PubMed:7623806, PubMed:7859290). Regulates IL6 expression in B cells as POU2F2/OCT2 coactivator (By similarity)