Fascin (55 kDa actin-bundling protein) (Singed-like protein) (p55)
1_MTANG 6_ TAEAV 11_ QIQFG 16_ LINCG 21_ NKYLT 26_ AEAFG 31_ FKVNA 36_ SASSL 41_ KKKQI 46_ WTLEQ 51_ PPDEA 56_ GSAAV 61_ CLRSH 66_ LGRYL 71_ AADKD 76_ GNVTC 81_ EREVP 86_ GPDCR 91_ FLIVA 96_ HDDGR 101_ WSLQS 106_ EAHRR 111_ YFGGT 116_ EDRLS 121_ CFAQT 126_ VSPAE 131_ KWSVH 136_ IAMHP 141_ QVNIY 146_ SVTRK 151_ RYAHL 156_ SARPA 161_ DEIAV 166_ DRDVP 171_ WGVDS 176_ LITLA 181_ FQDQR 186_ YSVQT 191_ ADHRF 196_ LRHDG 201_ RLVAR 206_ PEPAT 211_ GYTLE 216_ FRSGK 221_ VAFRD 226_ CEGRY 231_ LAPSG 236_ PSGTL 241_ KAGKA 246_ TKVGK 251_ DELFA 256_ LEQSC 261_ AQVVL 266_ QAANE 271_ RNVST 276_ RQGMD 281_ LSANQ 286_ DEETD 291_ QETFQ 296_ LEIDR 301_ DTKKC 306_ AFRTH 311_ TGKYW 316_ TLTAT 321_ GGVQS 326_ TASSK 331_ NASCY 336_ FDIEW 341_ RDRRI 346_ TLRAS 351_ NGKFV 356_ TSKKN 361_ GQLAA 366_ SVETA 371_ GDSEL 376_ FLMKL 381_ INRPI 386_ IVFRG 391_ EHGFI 396_ GCRKV 401_ TGTLD 406_ ANRSS 411_ YDVFQ 416_ LEFND 421_ GAYNI 426_ KDSTG 431_ KYWTV 436_ GSDSA 441_ VTSSG 446_ DTPVD 451_ FFFEF 456_ CDYNK 461_ VAIKV 466_ GGRYL 471_ KGDHA 476_ GVLKA 481_ SAETV 486_DPASL
1: Actin-binding protein that contains 2 major actin binding sites (PubMed:21685497, PubMed:23184945). Organizes filamentous actin into parallel bundles (PubMed:20393565, PubMed:21685497, PubMed:23184945). Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers (PubMed:22155786). Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration (PubMed:20393565, PubMed:21685497, PubMed:23184945). Mediates reorganization of the actin cytoskeleton and axon growth cone collapse in response to NGF (PubMed:22155786)