Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.16) (EC 3.1.3.48) (CDK2-associated dual-specificity phosphatase) (Cyclin-dependent kinase interactor 1) (Cyclin-dependent kinase-interacting protein 2) (Kinase-associated phosphatase)
1_MKPPS 6_ SIQTS 11_ EFDSS 16_ DEEPI 21_ EDEQT 26_ PIHIS 31_ WLSLS 36_ RVNCS 41_ QFLGL 46_ CALPG 51_ CKFKD 56_ VRRNV 61_ QKDTE 66_ ELKSC 71_ GIQDI 76_ FVFCT 81_ RGELS 86_ KYRVP 91_ NLLDL 96_ YQQCG 101_ IITHH 106_ HPIAD 111_ GGTPD 116_ IASCC 121_ EIMEE 126_ LTTCL 131_ KNYRK 136_ TLIHC 141_ YGGLG 146_ RSCLV 151_ AACLL 156_ LYLSD 161_ TISPE 166_ QAIDS 171_ LRDLR 176_ GSGAI 181_ QTIKQ 186_ YNYLH 191_ EFRDK 196_ LAAHL 201_ SSRDS 206_QSRSV
1: May play a role in cell cycle regulation. Dual specificity CC phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues (PubMed:8127873, PubMed:8242750). Dephosphorylates CDK2 at 'Thr-160' in a cyclin-dependent manner (PubMed:7569954)