Histone H3.1t (H3/t) (H3t) (H3/g) (Histone H3.4)
1_MARTK 6_ QTARK 11_ STGGK 16_ APRKQ 21_ LATKV 26_ ARKSA 31_ PATGG 36_ VKKPH 41_ RYRPG 46_ TVALR 51_ EIRRY 56_ QKSTE 61_ LLIRK 66_ LPFQR 71_ LMREI 76_ AQDFK 81_ TDLRF 86_ QSSAV 91_ MALQE 96_ ACESY 101_ LVGLF 106_ EDTNL 111_ CVIHA 116_ KRVTI 121_ MPKDI 126_ QLARR 131_IRGER
1: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling