Cytochrome P450 2A13 (EC 1.14.14.1) (CYPIIA13)
1_MLASG 6_ LLLVT 11_ LLACL 16_ TVMVL 21_ MSVWR 26_ QRKSR 31_ GKLPP 36_ GPTPL 41_ PFIGN 46_ YLQLN 51_ TEQMY 56_ NSLMK 61_ ISERY 66_ GPVFT 71_ IHLGP 76_ RRVVV 81_ LCGHD 86_ AVKEA 91_ LVDQA 96_ EEFSG 101_ RGEQA 106_ TFDWL 111_ FKGYG 116_ VAFSN 121_ GERAK 126_ QLRRF 131_ SIATL 136_ RGFGV 141_ GKRGI 146_ EERIQ 151_ EEAGF 156_ LIDAL 161_ RGTHG 166_ ANIDP 171_ TFFLS 176_ RTVSN 181_ VISSI 186_ VFGDR 191_ FDYED 196_ KEFLS 201_ LLRMM 206_ LGSFQ 211_ FTATS 216_ TGQLY 221_ EMFSS 226_ VMKHL 231_ PGPQQ 236_ QAFKE 241_ LQGLE 246_ DFIAK 251_ KVEHN 256_ QRTLD 261_ PNSPR 266_ DFIDS 271_ FLIRM 276_ QEEEK 281_ NPNTE 286_ FYLKN 291_ LVMTT 296_ LNLFF 301_ AGTET 306_ VSTTL 311_ RYGFL 316_ LLMKH 321_ PEVEA 326_ KVHEE 331_ IDRVI 336_ GKNRQ 341_ PKFED 346_ RAKMP 351_ YTEAV 356_ IHEIQ 361_ RFGDM 366_ LPMGL 371_ AHRVN 376_ KDTKF 381_ RDFFL 386_ PKGTE 391_ VFPML 396_ GSVLR 401_ DPRFF 406_ SNPRD 411_ FNPQH 416_ FLDKK 421_ GQFKK 426_ SDAFV 431_ PFSIG 436_ KRYCF 441_ GEGLA 446_ RMELF 451_ LFFTT 456_ IMQNF 461_ RFKSP 466_ QSPKD 471_ IDVSP 476_ KHVGF 481_ ATIPR 486_NYTMS
1: Exhibits a coumarin 7-hydroxylase activity. Active in the metabolic activation of hexamethylphosphoramide, N,N-dimethylaniline, 2'-methoxyacetophenone, N-nitrosomethylphenylamine, and the tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Possesses phenacetin O-deethylation activity