2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial (EC 1.3.1.124) (2,4-dienoyl-CoA reductase [NADPH]) (4-enoyl-CoA reductase [NADPH]) (Short chain dehydrogenase/reductase family 18C member 1)
1_MKLPA 6_ RVFFT 11_ LGSRL 16_ PCGLA 21_ PRRFF 26_ SYGTK 31_ ILYQN 36_ TEALQ 41_ SKFFS 46_ PLQKA 51_ MLPPN 56_ SFQGK 61_ VAFIT 66_ GGGTG 71_ LGKGM 76_ TTLLS 81_ SLGAQ 86_ CVIAS 91_ RKMDV 96_ LKATA 101_ EQISS 106_ QTGNK 111_ VHAIQ 116_ CDVRD 121_ PDMVQ 126_ NTVSE 131_ LIKVA 136_ GHPNI 141_ VINNA 146_ AGNFI 151_ SPTER 156_ LSPNA 161_ WKTIT 166_ DIVLN 171_ GTAFV 176_ TLEIG 181_ KQLIK 186_ AQKGA 191_ AFLSI 196_ TTIYA 201_ ETGSG 206_ FVVPS 211_ ASAKA 216_ GVEAM 221_ SKSLA 226_ AEWGK 231_ YGMRF 236_ NVIQP 241_ GPIKT 246_ KGAFS 251_ RLDPT 256_ GTFEK 261_ EMIGR 266_ IPCGR 271_ LGTVE 276_ ELANL 281_ AAFLC 286_ SDYAS 291_ WINGA 296_ VIKFD 301_ GGEEV 306_ LISGE 311_ FNDLR 316_ KVTKE 321_ QWDTI 326_EELIR
1: Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in mitochondria. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA