Diacylglycerol kinase delta (DAG kinase delta) (EC 2.7.1.107) (130 kDa diacylglycerol kinase) (Diglyceride kinase delta) (DGK-delta)
1_MAAAA 6_ GAPPP 11_ GPPQP 16_ PPPPP 21_ PEESS 26_ DSEPE 31_ AEPGS 36_ PQKLI 41_ RKVST 46_ SGQIR 51_ QKTII 56_ KEGML 61_ TKQNN 66_ SFQRS 71_ KRRYF 76_ KLRGR 81_ TLYYA 86_ KTAKS 91_ IIFDE 96_ VDLTD 101_ ASVAE 106_ SSTKN 111_ VNNSF 116_ TVITP 121_ CRKLI 126_ LCADN 131_ RKEME 136_ DWIAA 141_ LKTVQ 146_ NREHF 151_ EPTQY 156_ SMDHF 161_ SGMHN 166_ WYACS 171_ HARPT 176_ YCNVC 181_ REALS 186_ GVTSH 191_ GLSCE 196_ VCKFK 201_ AHKRC 206_ AVRAT 211_ NNCKW 216_ TTLAS 221_ IGKDI 226_ IEDAD 231_ GIAMP 236_ HQWLE 241_ GNLPV 246_ SAKCT 251_ VCDKT 256_ CGSVL 261_ RLQDW 266_ RCLWC 271_ KAMVH 276_ TSCKE 281_ SLLTK 286_ CPLGL 291_ CKVSV 296_ IPPTA 301_ LNSID 306_ SDGFW 311_ KASCP 316_ PSCTS 321_ PLLVF 326_ VNSKS 331_ GDNQG 336_ VKFLR 341_ RFKQL 346_ LNPAQ 351_ VFDLM 356_ NGGPH 361_ LGLRL 366_ FQKFD 371_ TFRIL 376_ VCGGD 381_ GSVGW 386_ VLSEI 391_ DSLNL 396_ HKQCQ 401_ LGVLP 406_ LGTGN 411_ DLARV 416_ LGWGS 421_ ACDDD 426_ TQLPQ 431_ ILEKL 436_ ERAST 441_ KMLDR 446_ WSVMA 451_ YEAKL 456_ PRQAS 461_ SSTVT 466_ EDFSE 471_ DSEVQ 476_ QILFY 481_ EDSVA 486_ AHLSK 491_ ILTSD 496_ QHSVV 501_ ISSAK 506_ VLCET 511_ VKDFV 516_ ARVGK 521_ AYEKT 526_ TESSE 531_ ESEVM 536_ AKKCS 541_ VLKEK 546_ LDSLL 551_ KTLDD 556_ ESQAS 561_ SSLPN 566_ PPPTI 571_ AEEAE 576_ DGDGS 581_ GSICG 586_ STGDR 591_ LVASA 596_ CPARP 601_ QIFRP 606_ REQLM 611_ LRANS 616_ LKKAI 621_ RQIIE 626_ HTEKA 631_ VDEQN 636_ AQTQE 641_ QEGFV 646_ LGLSE 651_ SEEKM 656_ DHRVC 661_ PPLSH 666_ SESFG 671_ VPKGR 676_ SQRKV 681_ SKSPC 686_ EKLIS 691_ KGSLS 696_ LGSSA 701_ SLPPQ 706_ PGSRD 711_ GLPAL 716_ NTKIL 721_ YPNVR 726_ AGMSG 731_ SLPGG 736_ SVISR 741_ LLINA 746_ DPFNS 751_ EPETL 756_ EYYTE 761_ KCVMN 766_ NYFGI 771_ GLDAK 776_ ISLDF 781_ NNKRD 786_ EHPEK 791_ CRSRT 796_ KNMMW 801_ YGVLG 806_ TKELL 811_ HRTYK 816_ NLEQK 821_ VLLEC 826_ DGRPI 831_ PLPSL 836_ QGIAV 841_ LNIPS 846_ YAGGT 851_ NFWGG 856_ TKEDD 861_ TFAAP 866_ SFDDK 871_ ILEVV 876_ AVFGS 881_ MQMAV 886_ SRVIR 891_ LQHHR 896_ IAQCR 901_ TVKIS 906_ ILGDE 911_ GVPVQ 916_ VDGEA 921_ WVQPP 926_ GYIRI 931_ VHKNR 936_ AQTLT 941_ RDRAF 946_ ESTLK 951_ SWEDK 956_ QKCEL 961_ PRPPS 966_ CSLHP 971_ EMLSE 976_ EEATQ 981_ MDQFG 986_ QAAGV 991_ LIHSI 996_ REIAQ 1001_ SHRDM 1006_ EQELA 1011_ HAVNA 1016_ SSKSM 1021_ DRVYG 1026_ KPRTT 1031_ EGLNC 1036_ SFVLE 1041_ MVNNF 1046_ RALRS 1051_ ETELL 1056_ LSGKM 1061_ ALQLD 1066_ PPQKE 1071_ QLGSA 1076_ LAEMD 1081_ RQLRR 1086_ LADTP 1091_ WLCQS 1096_ AEPGD 1101_ EESVM 1106_ LDLAK 1111_ RSRSG 1116_ KFRLV 1121_ TKFKK 1126_ EKNNK 1131_ NKEAH 1136_ SSLGA 1141_ PVHLW 1146_ GTEEV 1151_ AAWLE 1156_ HLSLC 1161_ EYKDI 1166_ FTRHD 1171_ IRGSE 1176_ LLHLE 1181_ RRDLK 1186_ DLGVT 1191_ KVGHM 1196_ KRILC 1201_ GIKEL 1206_SRSAP
1: Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids (PubMed:12200442, PubMed:23949095). Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (Probable). By controlling the levels of diacylglycerol, regulates for instance the PKC and EGF receptor signaling pathways and plays a crucial role during development (By similarity). May also regulate clathrin-dependent endocytosis (PubMed:17880279)