Gene name: IMMT

Uniprot entry:

Q16891

Protein names:

MICOS complex subunit MIC60 (Cell proliferation-inducing gene 4/52 protein) (Mitochondrial inner membrane protein) (Mitofilin) (p87/89)

Protein sequence:

1_MLRAC 6_ QLSGV 11_ TAAAQ 16_ SCLCG 21_ KFVLR 26_ PLRPC 31_ RRYST 36_ SGSSG 41_ LTTGK 46_ IAGAG 51_ LLFVG 56_ GGIGG 61_ TILYA 66_ KWDSH 71_ FRESV 76_ EKTIP 81_ YSDKL 86_ FEMVL 91_ GPAAY 96_ NVPLP 101_ KKSIQ 106_ SGPLK 111_ ISSVS 116_ EVMKE 121_ SKQPA 126_ SQLQK 131_ QKGDT 136_ PASAT 141_ APTEA 146_ AQIIS 151_ AAGDT 156_ LSVPA 161_ PAVQP 166_ EESLK 171_ TDHPE 176_ IGEGK 181_ PTPAL 186_ SEEAS 191_ SSSIR 196_ ERPPE 201_ EVAAR 206_ LAQQE 211_ KQEQV 216_ KIESL 221_ AKSLE 226_ DALRQ 231_ TASVT 236_ LQAIA 241_ AQNAA 246_ VQAVN 251_ AHSNI 256_ LKAAM 261_ DNSEI 266_ AGEKK 271_ SAQWR 276_ TVEGA 281_ LKERR 286_ KAVDE 291_ AADAL 296_ LKAKE 301_ ELEKM 306_ KSVIE 311_ NAKKK 316_ EVAGA 321_ KPHIT 326_ AAEGK 331_ LHNMI 336_ VDLDN 341_ VVKKV 346_ QAAQS 351_ EAKVV 356_ SQYHE 361_ LVVQA 366_ RDDFK 371_ RELDS 376_ ITPEV 381_ LPGWK 386_ GMSVS 391_ DLADK 396_ LSTDD 401_ LNSLI 406_ AHAHR 411_ RIDQL 416_ NRELA 421_ EQKAT 426_ EKQHI 431_ TLALE 436_ KQKLE 441_ EKRAF 446_ DSAVA 451_ KALEH 456_ HRSEI 461_ QAEQD 466_ RKIEE 471_ VRDAM 476_ ENEMR 481_ TQLRR 486_ QAAAH 491_ TDHLR 496_ DVLRV 501_ QEQEL 506_ KSEFE 511_ QNLSE 516_ KLSEQ 521_ ELQFR 526_ RLSQE 531_ QVDNF 536_ TLDIN 541_ TAYAR 546_ LRGIE 551_ QAVQS 556_ HAVAE 561_ EEARK 566_ AHQLW 571_ LSVEA 576_ LKYSM 581_ KTSSA 586_ ETPTI 591_ PLGSA 596_ VEAIK 601_ ANCSD 606_ NEFTQ 611_ ALTAA 616_ IPPES 621_ LTRGV 626_ YSEET 631_ LRARF 636_ YAVQK 641_ LARRV 646_ AMIDE 651_ TRNSL 656_ YQYFL 661_ SYLQS 666_ LLLFP 671_ PQQLK 676_ PPPEL 681_ CPEDI 686_ NTFKL 691_ LSYAS 696_ YCIEH 701_ GDLEL 706_ AAKFV 711_ NQLKG 716_ ESRRV 721_ AQDWL 726_ KEARM 731_ TLETK 736_ QIVEI 741_ LTAYA 746_ SAVGI 751_GTTQV

Protein annotations

Protein functions:

1: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane (PubMed:22114354, PubMed:25781180, PubMed:32567732, PubMed:33130824). Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed:22114354, PubMed:25781180, PubMed:32567732, PubMed:33130824)