Endothelial cell-specific chemotaxis regulator (Apoptosis regulator through modulating IAP expression) (ARIA) (Endothelial cell-specific molecule 2)
1_MGTAG 6_ AMQLC 11_ WVILG 16_ FLLFR 21_ GHNSQ 26_ PTMTQ 31_ TSSSQ 36_ GGLGG 41_ LSLTT 46_ EPVSS 51_ NPGYI 56_ PSSEA 61_ NRPSH 66_ LSSTG 71_ TPGAG 76_ VPSSG 81_ RDGGT 86_ SRDTF 91_ QTVPP 96_ NSTTM 101_ SLSMR 106_ EDATI 111_ LPSPT 116_ SETVL 121_ TVAAF 126_ GVISF 131_ IVILV 136_ VVVII 141_ LVGVV 146_ SLRFK 151_ CRKSK 156_ ESEDP 161_ QKPGS 166_ SGLSE 171_ SCSTA 176_ NGEKD 181_ SITLI 186_ SMKNI 191_ NMNNG 196_KQSLS
1: Regulates endothelial chemotaxis and tube formation. Has a role in angiogenesis and apoptosis via modulation of the actin cytoskeleton and facilitation of proteasomal degradation of the apoptosis inhibitors BIRC3/IAP1 and BIRC2/IAP2