Glutamine and serine-rich protein 1
1_MNFLS 6_ TAESR 11_ TAQAA 16_ ASGTT 21_ LLPQF 26_ RAPSW 31_ QTGMH 36_ SSAAT 41_ ELFAT 46_ GPLPS 51_ TGTLP 56_ PSLSA 61_ YQHPT 66_ TFSNR 71_ NFATT 76_ SPLVL 81_ QDSTF 86_ NTTSN 91_ GILSH 96_ HDPLL 101_ QIKTS 106_ QGTVP 111_ TALAF 116_ ERLGS 121_ SVLSN 126_ SIPPQ 131_ SSTYR 136_ SAQES 141_ APHLL 146_ QPQFS 151_ LLPSA 156_ LGGSQ 161_ QTPQA 166_ YSSTL 171_ FTSST 176_ ASIER 181_ ALLRE 186_ CSVIK 191_ HHQRP 196_ SGTQS 201_ IQAQL 206_ TGSQH 211_ SLHSY 216_ LSNSS 221_ VVNFQ 226_ ETTRQ 231_ SSLSC 236_ SPIGD 241_ STQVS 246_ NGGLQ 251_ QKTSQ 256_ VSVEL 261_ AQSYS 266_ SAIPS 271_ SGYPP 276_ STTKI 281_ KSCST 286_ EQPLT 291_ STKTP 296_ KPQSI 301_ IPPVQ 306_ TLSYS 311_ KPLHN 316_ QSSVI 321_ SGQAQ 326_ IYSTA 331_ QLPSL 336_ LSVSQ 341_ SQNYG 346_ LVQPH 351_ NVPSI 356_ VHSQV 361_ YRSSK 366_ VEKLP 371_ PLYKT 376_ LTFSG 381_ SSQTV 386_ TPENQ 391_ TLNYS 396_ SNQQE 401_ VLSSV 406_ TNENY 411_ PAQTR 416_ DLSSV 421_ SQSQS 426_ YSSGH 431_ SQGLS 436_ PVSQT 441_ QVSYS 446_ SQSQV 451_ LSVVS 456_ LSESY 461_ ASGES 466_ LTLTA 471_ PSLSY 476_ SSASR 481_ AQNLP 486_ DSSPT 491_ QNYIS 496_ MHSSQ 501_ NVQTQ 506_ ESSSP 511_ QSQKF 516_ LPAVQ 521_ SSSFA 526_ SSTHC 531_ QTLQN 536_ NITSP 541_ DPKSY 546_ AERKL 551_ DSDVY 556_ PSSKQ 561_ EDGFP 566_ MQELQ 571_ VLQPQ 576_ ASLES 581_ STQRL 586_ SDGEI 591_ NAQES 596_ TYKVS 601_ KADDR 606_ YSQSV 611_ IRSNS 616_ RLEDQ 621_ VIGVA 626_ LQASK 631_ KEESV 636_ VGSVT 641_ QLNQQ 646_ IGQVN 651_ NAATL 656_ DLKNS 661_ TNLIQ 666_ TPQIR 671_ LNTKD 676_ LKQQH 681_ PLILK 686_ VHESK 691_ VQEQH 696_ DQIIN 701_ ASSQI 706_ QIPNH 711_ ALGHG 716_ HQASL 721_ PNTQV 726_ LLDSA 731_ CDLQI 736_ LQQSI 741_ LQAGL 746_ GQVKA 751_ SLQAQ 756_ RVQSP 761_ QQIVH 766_ PFLQM 771_ EGHVI 776_ QSNGD 781_ HSQQQ 786_ LHPQN 791_ SEVMK 796_ MDLSE 801_ SSKPL 806_ QQHLT 811_ TKGHF 816_ SETNQ 821_ HDSKN 826_ QFVSL 831_ GSMCF 836_ PEAVL 841_ LSDER 846_ NILSN 851_ VDDIL 856_ AATAA 861_ ACGVT 866_ PTDFS 871_ KSTSN 876_ ETMQA 881_ VEDGD 886_ SKSHF 891_ QQSLD 896_ VRHVT 901_ SDFNS 906_ MTATV 911_ GKPQN 916_ INDTS 921_ LNGNQ 926_ VTVNL 931_ SPVPA 936_ LQSKM 941_ TLDQQ 946_ HIETP 951_ GQNIP 956_ TKVTS 961_ AVVGP 966_ SHEVQ 971_ EQSSG 976_ PFKKQ 981_ SATNL 986_ ESEED 991_ SEAPV 996_ DSTLN 1001_ NNRNQ 1006_ EFVSS 1011_ SRSIS 1016_ GENAT 1021_ SESEF 1026_ TLGGD 1031_ DSGVS 1036_ MNPAR 1041_ SALAL 1046_ LAMAQ 1051_ SGDAV 1056_ SVKIE 1061_ EENQD 1066_ LMHFN 1071_ LQKKR 1076_ AKGKG 1081_ QVKEE 1086_ DNSNQ 1091_ KQLKR 1096_ PAQGK 1101_ RQNPR 1106_ GTDIY 1111_ LPYTP 1116_ PSSES 1121_ CHDGY 1126_ QHQEK 1131_ MRQKI 1136_ KEVEE 1141_ KQPEV 1146_ KTGFI 1151_ ASFLD 1156_ FLKSG 1161_ PKQQF 1166_ STLAV 1171_ RMPNR 1176_ TRRPG 1181_ TQMVR 1186_ TFCPP 1191_ PLPKP 1196_ SSTTP 1201_ TPLVS 1206_ ETGGN 1211_ SPSDK 1216_ VDNEL 1221_ KNLEH 1226_ LSSFS 1231_ SDEDD 1236_ PGYSQ 1241_ DAYKS 1246_ VSTPL 1251_ TTLDA 1256_ TSDKK 1261_ KKTEA 1266_ LQVAT 1271_ TSPTA 1276_ NTTGT 1281_ ATTSS 1286_ TTVGA 1291_ VKQEP 1296_ LHSTS 1301_ YAVNI 1306_ LENIS 1311_ SSESS 1316_ KPIEL 1321_ DGLPS 1326_ DQFAK 1331_ GQDTV 1336_ AIEGF 1341_ TDEED 1346_ TESGG 1351_ EGQYR 1356_ ERDEF 1361_ VVKIE 1366_ DIETF 1371_ KEALK 1376_ TGKEP 1381_ PAIWK 1386_ VQKAL 1391_ LQKFV 1396_ PEIRD 1401_ GQREF 1406_ AATNS 1411_ YLGYF 1416_ GDAKS 1421_ KYKRI 1426_ YVKFI 1431_ ENANK 1436_ KEYVR 1441_ VCSKK 1446_ PRNKP 1451_ SQTIR 1456_ TVQAK 1461_ PSSSS 1466_ KTSDP 1471_ LASKT 1476_ TTTKA 1481_ PSVKP 1486_ KVKQP 1491_ KVKAE 1496_ PPPKK 1501_ RKKWK 1506_ EEFSS 1511_ SQSDS 1516_ SPEIH 1521_ TSSSD 1526_ DEEFE 1531_ PPAPF 1536_ VTRFL 1541_ NTRAM 1546_ KETFK 1551_ SYMEL 1556_ LVSIA 1561_ LDPDT 1566_ MQALE 1571_ KSNDE 1576_ LLLPH 1581_ MKKID 1586_ GMLND 1591_ NRKRL 1596_ LLNLH 1601_ LDQSF 1606_ KNALE 1611_ SFPEL 1616_ TIITR 1621_ DSKAK 1626_ SGGTA 1631_ ISKIK 1636_ MNGKA 1641_ YNKKT 1646_ LRTSK 1651_ TTTKS 1656_ AQEFA 1661_ VDPEK 1666_ IQLYS 1671_ LYHSL 1676_ HHYKY 1681_ HVYLI 1686_ CKDEI 1691_ SSVQK 1696_ KNEDL 1701_ GQEEI 1706_ VQLCM 1711_ KNVKW 1716_ VEDLF 1721_ EKFGE 1726_LLNHV
1: Plays an essential role in the protection and maintenance of transcriptional and developmental programs. Protects many bivalent promoters and poised enhancers from hypermethylation, showing a marked preference for these regulatory elements over other types of promoters or enhancers. Mechanistically, cooperates with TET1 and binds to DNA in a common complex to inhibit the binding of DNMT3A/3B and therefore de novo methylation