Hyaluronidase-4 (Hyal-4) (EC 3.2.1.35) (Chondroitin sulfate endo-beta-N-acetylgalactosaminidase) (Chondroitin sulfate hydrolase) (CSHY) (Hyaluronoglucosaminidase-4)
1_MKVLS 6_ EGQLK 11_ LCVVQ 16_ PVHLT 21_ SWLLI 26_ FFILK 31_ SISCL 36_ KPARL 41_ PIYQR 46_ KPFIA 51_ AWNAP 56_ TDQCL 61_ IKYNL 66_ RLNLK 71_ MFPVI 76_ GSPLA 81_ KARGQ 86_ NVTIF 91_ YVNRL 96_ GYYPW 101_ YTSQG 106_ VPING 111_ GLPQN 116_ ISLQV 121_ HLEKA 126_ DQDIN 131_ YYIPA 136_ EDFSG 141_ LAVID 146_ WEYWR 151_ PQWAR 156_ NWNSK 161_ DVYRQ 166_ KSRKL 171_ ISDMG 176_ KNVSA 181_ TDIEY 186_ LAKVT 191_ FEESA 196_ KAFMK 201_ ETIKL 206_ GIKSR 211_ PKGLW 216_ GYYLY 221_ PDCHN 226_ YNVYA 231_ PNYSG 236_ SCPED 241_ EVLRN 246_ NELSW 251_ LWNSS 256_ AALYP 261_ SIGVW 266_ KSLGD 271_ SENIL 276_ RFSKF 281_ RVHES 286_ MRIST 291_ MTSHD 296_ YALPV 301_ FVYTR 306_ LGYRD 311_ EPLFF 316_ LSKQD 321_ LVSTI 326_ GESAA 331_ LGAAG 336_ IVIWG 341_ DMNLT 346_ ASKAN 351_ CTKVK 356_ QFVSS 361_ DLGSY 366_ IANVT 371_ RAAEV 376_ CSLHL 381_ CRNNG 386_ RCIRK 391_ MWNAP 396_ SYLHL 401_ NPASY 406_ HIEAS 411_ EDGEF 416_ TVKGK 421_ ASDTD 426_ LAVMA 431_ DTFSC 436_ HCYQG 441_ YEGAD 446_ CREIK 451_ TADGC 456_ SGVSP 461_ SPGSL 466_ MTLCL 471_ LLLAS 476_YRSIQ
1: Endo-hyaluronidase that degrades hyaluronan to smaller oligosaccharide fragments. Also has chondroitin sulfate hydrolase activity, The best substrate being the galactosaminidic linkage in the sequence of a trisulfated tetrasaccharide