Small G protein signaling modulator 1 (RUN and TBC1 domain-containing protein 2)
1_MASAP 6_ AEAET 11_ RQRLL 16_ RTVKK 21_ EVKQI 26_ MEEAV 31_ TRKFV 36_ HEDSS 41_ HIISF 46_ CAAVE 51_ ACVLH 56_ GLRRR 61_ AAGFL 66_ RSNKI 71_ AALFM 76_ KVGKN 81_ FPPAE 86_ DLSRK 91_ VQDLE 96_ QLIES 101_ ARNQI 106_ QGLQE 111_ NVRKL 116_ PKLPN 121_ LSPLA 126_ IKHLW 131_ IRTAL 136_ FEKVL 141_ DKIVH 146_ YLVEN 151_ SSKYY 156_ EKEAL 161_ LMDPV 166_ DGPIL 171_ ASLLV 176_ GPCAL 181_ EYTKM 186_ KTADH 191_ FWTDP 196_ SADEL 201_ VQRHR 206_ IHSSH 211_ VRQDS 216_ PTKRP 221_ ALCIQ 226_ KRHSS 231_ GSMDD 236_ RPSLS 241_ ARDYV 246_ ESLHQ 251_ NSRAT 256_ LLYGK 261_ NNVLV 266_ QPRDD 271_ MEAVP 276_ GYLSL 281_ HQTAD 286_ VMTLK 291_ WTPNQ 296_ LMNGS 301_ VGDLD 306_ YEKSV 311_ YWDYA 316_ MTIRL 321_ EEIVY 326_ LHCHQ 331_ QVDSG 336_ GTVVL 341_ VSQDG 346_ IQRPP 351_ FRFPK 356_ GGHLL 361_ QFLSC 366_ LENGL 371_ LPHGQ 376_ LDPPL 381_ WSQRG 386_ KGKVF 391_ PKLRK 396_ RSPQG 401_ SAEST 406_ SSDKD 411_ DDEAT 416_ DYVFR 421_ IIYPG 426_ MQSEF 431_ VAPDF 436_ LGSTS 441_ SVSVG 446_ PAWMM 451_ VPAGR 456_ SMLVV 461_ ARGSQ 466_ WEPAR 471_ WDTTL 476_ PTPSP 481_ KEQPP 486_ MPQDL 491_ MDVSV 496_ SNLPS 501_ LWQPS 506_ PRKSS 511_ CSSCS 516_ QSGSA 521_ DGSST 526_ NGCNH 531_ ERAPL 536_ KLLCD 541_ NMKYQ 546_ ILSRA 551_ FYGWL 556_ AYCRH 561_ LSTVR 566_ THLSA 571_ LVNHM 576_ IVSPD 581_ LPCDA 586_ GQGLT 591_ ARIWE 596_ QYLHD 601_ STSYE 606_ EQELL 611_ RLIYY 616_ GGIQP 621_ EIRKA 626_ VWPFL 631_ LGHYQ 636_ FGMTE 641_ TERKE 646_ VDEQI 651_ HACYA 656_ QTMAE 661_ WLGCE 666_ AIVRQ 671_ RERES 676_ HAAAL 681_ AKCSS 686_ GASLD 691_ SHLHR 696_ MLHRD 701_ STISN 706_ ESSQS 711_ CSSGR 716_ QNIRL 721_ HSDSS 726_ SSTQV 731_ FESVD 736_ EVEQV 741_ EAEGR 746_ LEEKQ 751_ PKIPN 756_ GNLVN 761_ GTCSP 766_ DSGHP 771_ SSHNF 776_ SSGLS 781_ EHSEP 786_ SLSTE 791_ DSVLD 796_ AQRNT 801_ PTVLR 806_ PRDGS 811_ VDDRQ 816_ SSEAT 821_ TSQDE 826_ APREE 831_ LAVQD 836_ SLESD 841_ LLANE 846_ SMDEF 851_ MSITG 856_ SLDMA 861_ LPEKD 866_ DVVME 871_ GWRSS 876_ ETEKH 881_ GQADS 886_ EDNLS 891_ EEPEM 896_ ESLFP 901_ ALASL 906_ AVTTS 911_ ANEVS 916_ PVSSS 921_ GVTYS 926_ PELLD 931_ LYTVN 936_ LHRIE 941_ KDVQR 946_ CDRNY 951_ WYFTP 956_ ANLEK 961_ LRNIM 966_ CSYIW 971_ QHIEI 976_ GYVQG 981_ MCDLL 986_ APLLV 991_ ILDDE 996_ ALAFS 1001_ CFTEL 1006_ MKRMN 1011_ QNFPH 1016_ GGAMD 1021_ THFAN 1026_ MRSLI 1031_ QILDS 1036_ ELFEL 1041_ MHQNG 1046_ DYTHF 1051_ YFCYR 1056_ WFLLD 1061_ FKREL 1066_ VYDDV 1071_ FLVWE 1076_ TIWAA 1081_ KHVSS 1086_ AHYVL 1091_ FIALA 1096_ LVEVY 1101_ RDIIL 1106_ ENNMD 1111_ FTDII 1116_ KFFNE 1121_ MAERH 1126_ NTKQV 1131_ LKLAR 1136_ DLVYK 1141_VQTLI
1: Interacts with numerous Rab family members, functioning as Rab effector for some, and as GTPase activator for others. Promotes GTP hydrolysis by RAB34 and RAB36. Probably functions as a GTPase effector with RAB9A and RAB9B; does not stimulate GTP hydrolysis with RAB9A and RAB9B