DNA excision repair protein ERCC-6-like (EC 3.6.4.12) (ATP-dependent helicase ERCC6-like) (PLK1-interacting checkpoint helicase) (Tumor antigen BJ-HCC-15)
1_MEASR 6_ RFPEA 11_ EALSP 16_ EQAAH 21_ YLRYV 26_ KEAKE 31_ ATKNG 36_ DLEEA 41_ FKLFN 46_ LAKDI 51_ FPNEK 56_ VLSRI 61_ QKIQE 66_ ALEEL 71_ AEQGD 76_ DEFTD 81_ VCNSG 86_ LLLYR 91_ ELHNQ 96_ LFEHQ 101_ KEGIA 106_ FLYSL 111_ YRDGR 116_ KGGIL 121_ ADDMG 126_ LGKTV 131_ QIIAF 136_ LSGMF 141_ DASLV 146_ NHVLL 151_ IMPTN 156_ LINTW 161_ VKEFI 166_ KWTPG 171_ MRVKT 176_ FHGPS 181_ KDERT 186_ RNLNR 191_ IQQRN 196_ GVIIT 201_ TYQML 206_ INNWQ 211_ QLSSF 216_ RGQEF 221_ VWDYV 226_ ILDEA 231_ HKIKT 236_ SSTKS 241_ AICAR 246_ AIPAS 251_ NRLLL 256_ TGTPI 261_ QNNLQ 266_ ELWSL 271_ FDFAC 276_ QGSLL 281_ GTLKT 286_ FKMEY 291_ ENPIT 296_ RAREK 301_ DATPG 306_ EKALG 311_ FKISE 316_ NLMAI 321_ IKPYF 326_ LRRTK 331_ EDVQK 336_ KKSSN 341_ PEARL 346_ NEKNP 351_ DVDAI 356_ CEMPS 361_ LSRKN 366_ DLIIW 371_ IRLVP 376_ LQEEI 381_ YRKFV 386_ SLDHI 391_ KELLM 396_ ETRSP 401_ LAELG 406_ VLKKL 411_ CDHPR 416_ LLSAR 421_ ACCLL 426_ NLGTF 431_ SAQDG 436_ NEGED 441_ SPDVD 446_ HIDQV 451_ TDDTL 456_ MEESG 461_ KMIFL 466_ MDLLK 471_ RLRDE 476_ GHQTL 481_ VFSQS 486_ RQILN 491_ IIERL 496_ LKNRH 501_ FKTLR 506_ IDGTV 511_ THLLE 516_ REKRI 521_ NLFQQ 526_ NKDYS 531_ VFLLT 536_ TQVGG 541_ VGLTL 546_ TAATR 551_ VVIFD 556_ PSWNP 561_ ATDAQ 566_ AVDRV 571_ YRIGQ 576_ KENVV 581_ VYRLI 586_ TCGTV 591_ EEKIY 596_ RRQVF 601_ KDSLI 606_ RQTTG 611_ EKKNP 616_ FRYFS 621_ KQELR 626_ ELFTI 631_ EDLQN 636_ SVTQL 641_ QLQSL 646_ HAAQR 651_ KSDIK 656_ LDEHI 661_ AYLQS 666_ LGIAG 671_ ISDHD 676_ LMYTC 681_ DLSVK 686_ EELDV 691_ VEESH 696_ YIQQR 701_ VQKAQ 706_ FLVEF 711_ ESQNK 716_ EFLME 721_ QQRTR 726_ NEGAW 731_ LREPV 736_ FPSST 741_ KKKCP 746_ KLNKP 751_ QPQPS 756_ PLLST 761_ HHTQE 766_ EDISS 771_ KMASV 776_ VIDDL 781_ PKEGE 786_ KQDLS 791_ SIKVN 796_ VTTLQ 801_ DGKGT 806_ GSADS 811_ IATLP 816_ KGFGS 821_ VEELC 826_ TNSSL 831_ GMEKS 836_ FATKN 841_ EAVQK 846_ ETLQE 851_ GPKQE 856_ ALQED 861_ PLESF 866_ NYVLS 871_ KSTKA 876_ DIGPN 881_ LDQLK 886_ DDEIL 891_ RHCNP 896_ WPIIS 901_ ITNES 906_ QNAES 911_ NVSII 916_ EIADD 921_ LSASH 926_ SALQD 931_ AQASE 936_ AKLEE 941_ EPSAS 946_ SPQYA 951_ CDFNL 956_ FLEDS 961_ ADNRQ 966_ NFSSQ 971_ SLEHV 976_ EKENS 981_ LCGSA 986_ PNSRA 991_ GFVHS 996_ KTCLS 1001_ WEFSE 1006_ KDDEP 1011_ EEVVV 1016_ KAKIR 1021_ SKARR 1026_ IVSDG 1031_ EDEDD 1036_ SFKDT 1041_ SSINP 1046_ FNTSL 1051_ FQFSS 1056_ VKQFD 1061_ ASTPK 1066_ NDISP 1071_ PGRFF 1076_ SSQIP 1081_ SSVNK 1086_ SMNSR 1091_ RSLAS 1096_ RRSLI 1101_ NMVLD 1106_ HVEDM 1111_ EERLD 1116_ DSSEA 1121_ KGPED 1126_ YPEEG 1131_ VEESS 1136_ GEASK 1141_ YTEED 1146_ PSGET 1151_ LSSEN 1156_ KSSWL 1161_ MTSKP 1166_ SALAQ 1171_ ETSLG 1176_ APEPL 1181_ SGEQL 1186_ VGSPQ 1191_ DKAAE 1196_ ATNDY 1201_ ETLVK 1206_ RGKEL 1211_ KECGK 1216_ IQEAL 1221_ NCLVK 1226_ ALDIK 1231_ SADPE 1236_ VMLLT 1241_LSLYK
1: DNA helicase that acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase (PubMed:17218258, PubMed:23973328). Functions as ATP-dependent DNA translocase (PubMed:23973328, PubMed:28977671). Can promote Holliday junction branch migration (in vitro) (PubMed:23973328)