Gene name: DPY19L1

Uniprot entry:

Q2PZI1

Protein names:

Probable C-mannosyltransferase DPY19L1 (EC 2.4.1.-) (Dpy-19-like protein 1) (Protein dpy-19 homolog 1)

Protein sequence:

1_MEGRP 6_ PPEGR 11_ PPPRP 16_ RTGRA 21_ PRGRR 26_ RAVFA 31_ AVLHW 36_ SHITH 41_ LFEND 46_ RHFSH 51_ LSTLE 56_ REMAF 61_ RTEMG 66_ LYYSY 71_ FKTIV 76_ EAPSF 81_ LNGVW 86_ MIMND 91_ KLTEY 96_ PLVIN 101_ TLKRF 106_ NLYPE 111_ VILAS 116_ WYRIY 121_ TKIMD 126_ LIGIQ 131_ TKICW 136_ TVTRG 141_ EGLSP 146_ IESCE 151_ GLGDP 156_ ACFYV 161_ AVIFI 166_ LNGLM 171_ MALFF 176_ IYGTY 181_ LSGSR 186_ LGGLV 191_ TVLCF 196_ FFNHG 201_ ECTRV 206_ MWTPP 211_ LRESF 216_ SYPFL 221_ VLQML 226_ LVTHI 231_ LRATK 236_ LYRGS 241_ LIALC 246_ ISNVF 251_ FMLPW 256_ QFAQF 261_ VLLTQ 266_ IASLF 271_ AVYVV 276_ GYIDI 281_ CKLRK 286_ IIYIH 291_ MISLA 296_ LCFVL 301_ MFGNS 306_ MLLTS 311_ YYASS 316_ LVIIW 321_ GILAM 326_ KPHFL 331_ KINVS 336_ ELSLW 341_ VIQGC 346_ FWLFG 351_ TVILK 356_ YLTSK 361_ IFGIA 366_ DDAHI 371_ GNLLT 376_ SKFFS 381_ YKDFD 386_ TLLYT 391_ CAAEF 396_ DFMEK 401_ ETPLR 406_ YTKTL 411_ LLPVV 416_ LVVFV 421_ AIVRK 426_ IISDM 431_ WGVLA 436_ KQQTH 441_ VRKHQ 446_ FDHGE 451_ LVYHA 456_ LQLLA 461_ YTALG 466_ ILIMR 471_ LKLFL 476_ TPHMC 481_ VMASL 486_ ICSRQ 491_ LFGWL 496_ FCKVH 501_ PGAIV 506_ FAILA 511_ AMSIQ 516_ GSANL 521_ QTQWN 526_ IVGEF 531_ SNLPQ 536_ EELIE 541_ WIKYS 546_ TKPDA 551_ VFAGA 556_ MPTMA 561_ SVKLS 566_ ALRPI 571_ VNHPH 576_ YEDAG 581_ LRART 586_ KIVYS 591_ MYSRK 596_ AAEEV 601_ KRELI 606_ KLKVN 611_ YYILE 616_ ESWCV 621_ RRSKP 626_ GCSMP 631_ EIWDV 636_ EDPAN 641_ AGKTP 646_ LCNLL 651_ VKDSK 656_ PHFTT 661_ VFQNS 666_VYKVL

Protein annotations

Protein functions:

1: C-mannosyltransferase that mediates the C-mannosylation tryptophan residues on target proteins. The reaction occurs on the luminal side of the endoplasmic reticulum and involves the transfer of a mannose unit from a dolichylphosphate mannose (Dol-P-Man) donor to an acceptor protein containing a WxxW consensus sequence (By similarity). C-mannosylates the first two tryptophans in the WxxWxxWxxC motif in thrombospondin (TSP) type-1 of UNC5A (By similarity). Regulates neurite extension during development (By similarity)