Electroneutral sodium bicarbonate exchanger 1 (Electroneutral Na(+)-driven Cl-HCO3 exchanger) (Solute carrier family 4 member 8) (k-NBC3)
1_MPAAG 6_ SNEPD 11_ GVLSY 16_ QRPDE 21_ EAVVD 26_ QGGTS 31_ TILNI 36_ HYEKE 41_ ELEGH 46_ RTLYV 51_ GVRMP 56_ LGRQS 61_ HRHHR 66_ THGQK 71_ HRRRG 76_ RGKGA 81_ SQGEE 86_ GLEAL 91_ AHDTP 96_ SQRVQ 101_ FILGT 106_ EEDEE 111_ HVPHE 116_ LFTEL 121_ DEICM 126_ KEGED 131_ AEWKE 136_ TARWL 141_ KFEED 146_ VEDGG 151_ ERWSK 156_ PYVAT 161_ LSLHS 166_ LFELR 171_ SCLIN 176_ GTVLL 181_ DMHAN 186_ SIEEI 191_ SDLIL 196_ DQQEL 201_ SSDLN 206_ DSMRV 211_ KVREA 216_ LLKKH 221_ HHQNE 226_ KKRNN 231_ LIPIV 236_ RSFAE 241_ VGKKQ 246_ SDPHL 251_ MDKHG 256_ QTVSP 261_ QSVPT 266_ TNLEV 271_ KNGVN 276_ CEHSP 281_ VDLSK 286_ VDLHF 291_ MKKIP 296_ TGAEA 301_ SNVLV 306_ GEVDI 311_ LDRPI 316_ VAFVR 321_ LSPAV 326_ LLSGL 331_ TEVPI 336_ PTRFL 341_ FILLG 346_ PVGKG 351_ QQYHE 356_ IGRSM 361_ ATIMT 366_ DEIFH 371_ DVAYK 376_ AKERD 381_ DLLAG 386_ IDEFL 391_ DQVTV 396_ LPPGE 401_ WDPSI 406_ RIEPP 411_ KNVPS 416_ QEKRK 421_ MPGVP 426_ NGNVC 431_ HIEQE 436_ PHGGH 441_ SGPEL 446_ QRTGR 451_ LFGGL 456_ VLDIK 461_ RKAPW 466_ YWSDY 471_ RDALS 476_ LQCLA 481_ SFLFL 486_ YCACM 491_ SPVIT 496_ FGGLL 501_ GEATE 506_ GRISA 511_ IESLF 516_ GASMT 521_ GIAYS 526_ LFAGQ 531_ ALTIL 536_ GSTGP 541_ VLVFE 546_ KILFK 551_ FCKDY 556_ ALSYL 561_ SLRAC 566_ IGLWT 571_ AFLCI 576_ VLVAT 581_ DASSL 586_ VCYIT 591_ RFTEE 596_ AFASL 601_ ICIIF 606_ IYEAI 611_ EKLIH 616_ LAETY 621_ PIHMH 626_ SQLDH 631_ LSLYY 636_ CRCTL 641_ PENPN 646_ NHTLQ 651_ YWKDH 656_ NIVTA 661_ EVHWA 666_ NLTVS 671_ ECQEM 676_ HGEFM 681_ GSACG 686_ HHGPY 691_ TPDVL 696_ FWSCI 701_ LFFTT 706_ FILSS 711_ TLKTF 716_ KTSRY 721_ FPTRV 726_ RSMVS 731_ DFAVF 736_ LTIFT 741_ MVIID 746_ FLIGV 751_ PSPKL 756_ QVPSV 761_ FKPTR 766_ DDRGW 771_ IINPI 776_ GPNPW 781_ WTVIA 786_ AIIPA 791_ LLCTI 796_ LIFMD 801_ QQITA 806_ VIINR 811_ KEHKL 816_ KKGCG 821_ YHLDL 826_ LMVAI 831_ MLGVC 836_ SIMGL 841_ PWFVA 846_ ATVLS 851_ ITHVN 856_ SLKLE 861_ SECSA 866_ PGEQP 871_ KFLGI 876_ REQRV 881_ TGLMI 886_ FVLMG 891_ CSVFM 896_ TAILK 901_ FIPMP 906_ VLYGV 911_ FLYMG 916_ VSSLQ 921_ GIQFF 926_ DRLKL 931_ FGMPA 936_ KHQPD 941_ FIYLR 946_ HVPLR 951_ KVHLF 956_ TLIQL 961_ TCLVL 966_ LWVIK 971_ ASPAA 976_ IVFPM 981_ MVLAL 986_ VFVRK 991_ VMDLC 996_ FSKRE 1001_ LSWLD 1006_ DLMPE 1011_ SKKKK 1016_ LDDAK 1021_ KKAKE 1026_ EEEAE 1031_ KMLEI 1036_ GGDKF 1041_ PLESR 1046_ KLLSS 1051_ PGKNI 1056_ SCRCD 1061_ PSEIN 1066_ ISDEM 1071_ PKTTV 1076_ WKALS 1081_ MNSGN 1086_AKEKS
1: Mediates electroneutral sodium- and carbonate-dependent chloride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1 (PubMed:18577713). Plays a major role in pH regulation in neurons (By similarity). Mediates sodium reabsorption in the renal cortical collecting ducts (By similarity)