Solute carrier family 10 member 6 (Sodium-dependent organic anion transporter)
1_MRANC 6_ SSSSA 11_ CPANS 16_ SEEEL 21_ PVGLE 26_ VHGNL 31_ ELVFT 36_ VVSTV 41_ MMGLL 46_ MFSLG 51_ CSVEI 56_ RKLWS 61_ HIRRP 66_ WGIAV 71_ GLLCQ 76_ FGLMP 81_ FTAYL 86_ LAISF 91_ SLKPV 96_ QAIAV 101_ LIMGC 106_ CPGGT 111_ ISNIF 116_ TFWVD 121_ GDMDL 126_ SISMT 131_ TCSTV 136_ AALGM 141_ MPLCI 146_ YLYTW 151_ SWSLQ 156_ QNLTI 161_ PYQNI 166_ GITLV 171_ CLTIP 176_ VAFGV 181_ YVNYR 186_ WPKQS 191_ KIILK 196_ IGAVV 201_ GGVLL 206_ LVVAV 211_ AGVVL 216_ AKGSW 221_ NSDIT 226_ LLTIS 231_ FIFPL 236_ IGHVT 241_ GFLLA 246_ LFTHQ 251_ SWQRC 256_ RTISL 261_ ETGAQ 266_ NIQMC 271_ ITMLQ 276_ LSFTA 281_ EHLVQ 286_ MLSFP 291_ LAYGL 296_ FQLID 301_ GFLIV 306_ AAYQT 311_ YKRRL 316_ KNKHG 321_ KKNSG 326_ CTEVC 331_ HTRKS 336_ TSSRE 341_ TNAFL 346_ EVNEE 351_ GAITP 356_ GPPGP 361_ MDCHR 366_ ALEPV 371_GHITS
1: Transports sulfoconjugated steroid hormones from the extracellular compartment into the cytosol in a sodium-dependent manner without hydrolysis (PubMed:17491011, PubMed:23667501, PubMed:24717977, PubMed:28951227). Steroid sulfate hormones are commonly considered to be biologically inactive metabolites, that may be activated by steroid sulfatases into free steroids (PubMed:23667501, PubMed:24717977). May play an important role by delivering sulfoconjugated steroids to specific target cells in reproductive organs (By similarity). May play a role transporting the estriol precursor 16alpha-hydroxydehydroepiandrosterone 3-sulfate (16a-OH-DHEAS) at the fetal blood vessel endothelium (PubMed:24717977). Can also transport other sulfoconjugated molecules such as taurolithocholic acid-3-sulfate and sulfoconjugated pyrenes (PubMed:17491011)