Gene name: ALKBH6

Uniprot entry:

Q3KRA9

Protein names:

Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 6)

Protein sequence:

1_MEEQD 6_ ARVPA 11_ LEPFR 16_ VEQAP 21_ PVIYY 26_ VPDFI 31_ SKEEE 36_ EYLLR 41_ QVFNA 46_ PKPKW 51_ TQLSG 56_ RKLQN 61_ WGGLP 66_ HPRGM 71_ VPERL 76_ PPWLQ 81_ RYVDK 86_ VSNLS 91_ LFGGL 96_ PANHV 101_ LVNQY 106_ LPGEG 111_ IMPHE 116_ DGPLY 121_ YPTVS 126_ TISLG 131_ SHTVL 136_ DFYEP 141_ RRPED 146_ DDPTE 151_ QPRPP 156_ PRPTT 161_ SLLLE 166_ PRSLL 171_ VLRGP 176_ AYTRL 181_ LHGIA 186_ AARVD 191_ ALDAA 196_ SSPPN 201_ AAACP 206_ SARPG 211_ ACLVR 216_ GTRVS 221_ LTIRR 226_ VPRVL 231_RAGLL

Protein annotations

Protein functions:

1: Probable Fe(2+)/2-oxoglutarate-dependent dioxygenase involved in oxidative demethylation of nucleic acids (PubMed:39845104). Binds nucleic acids with a preference for ssDNA or ssRNA to other types of DNAs (PubMed:35120926). May play a role in nucleic acid damage repair (PubMed:35120926)