Cell cycle control protein 50B (P4-ATPase flippase complex beta subunit TMEM30B) (Transmembrane protein 30B)
1_MTWSA 6_ TARGA 11_ HQPDN 16_ TAFTQ 21_ QRLPA 26_ WQPLL 31_ SASIA 36_ LPLFF 41_ CAGLA 46_ FIGLG 51_ LGLYY 56_ SSNGI 61_ KELEY 66_ DYTGD 71_ PGTGN 76_ CSVCA 81_ AAGQG 86_ RALPP 91_ PCSCA 96_ WYFSL 101_ PELFQ 106_ GPVYL 111_ YYELT 116_ NFYQN 121_ NRRYG 126_ VSRDD 131_ AQLSG 136_ LPSAL 141_ RHPVN 146_ ECAPY 151_ QRSAA 156_ GLPIA 161_ PCGAI 166_ ANSLF 171_ NDSFS 176_ LWHQR 181_ QPGGP 186_ YVEVP 191_ LDRSG 196_ IAWWT 201_ DYHVK 206_ FRNPP 211_ LVNGS 216_ LALAF 221_ QGTAP 226_ PPNWR 231_ RPVYE 236_ LSPDP 241_ NNTGF 246_ INQDF 251_ VVWMR 256_ TAALP 261_ TFRKL 266_ YARIR 271_ QGNYS 276_ AGLPR 281_ GAYRV 286_ NITYN 291_ YPVRA 296_ FGGHK 301_ LLIFS 306_ SISWM 311_ GGKNP 316_ FLGIA 321_ YLVVG 326_ SLCIL 331_ TGFVM 336_ LVVYI 341_ RYQDQ 346_DDDDE
1: Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation also seems to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate (Probable). Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to the plasma membrane