ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1)
1_MFSLM 6_ ASCCG 11_ WFKRW 16_ REPVR 21_ KVTLL 26_ MVGLD 31_ NAGKT 36_ ATAKG 41_ IQGEY 46_ PEDVA 51_ PTVGF 56_ SKINL 61_ RQGKF 66_ EVTIF 71_ DLGGG 76_ IRIRG 81_ IWKNY 86_ YAESY 91_ GVIFV 96_ VDSSD 101_ EERME 106_ ETKEA 111_ MSEML 116_ RHPRI 121_ SGKPI 126_ LVLAN 131_ KQDKE 136_ GALGE 141_ ADVIE 146_ CLSLE 151_ KLVNE 156_ HKCLC 161_ QIEPC 166_ SAISG 171_ YGKKI 176_ DKSIK 181_ KGLYW 186_ LLHVI 191_ ARDFD 196_ ALNER 201_ IQKET 206_ TEQRA 211_ LEEQE 216_ KQERA 221_ ERVRK 226_ LREER 231_ KQNEQ 236_ EQAEL 241_ DGTSG 246_ LAELD 251_ PEPTN 256_ PFQPI 261_ ASVII 266_ ENEGK 271_ LEREK 276_ KNQKM 281_ EKDSD 286_ GCHLK 291_ HKMEH 296_ EQIET 301_ QGQVN 306_ HNGQK 311_ NNEFG 316_ LVENY 321_ KEALT 326_ QQLKN 331_ EDETD 336_ RPSLE 341_ SANGK 346_ KKTKK 351_ LRMKR 356_ NHRVE 361_ PLNID 366_ DCAPE 371_ SPTPP 376_ PPPPP 381_ VGWGT 386_ PKVTR 391_ LPKLE 396_ PLGET 401_ HHNDF 406_ YRKPL 411_ PPLAV 416_ PQRPN 421_SDAHD
1: Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze fit; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic interneurons in the developing cerebral cortex. Plays a role in ciliar trafficking of phosphatidylinositol phosphatase INPP5E in ciliogenesis (PubMed:38219074). May regulate ARF6- and RAB22A-dependent endocytic recycling traffic (PubMed:23223633)