Gene name: SLC25A52

Uniprot entry:

Q3SY17

Protein names:

Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A52 (Mitochondrial NAD(+) transporter SLC25A52) (Mitochondrial carrier triple repeat protein 2) (Solute carrier family 25 member 52)

Protein sequence:

1_MIDSE 6_ AHEKR 11_ PPILT 16_ SSKQD 21_ ISPHI 26_ TNVGE 31_ MKHYL 36_ CGCCA 41_ AFNNV 46_ AITYP 51_ IQKVL 56_ FRQQL 61_ YGIKT 66_ RDAVL 71_ QLRRD 76_ GFRNL 81_ YRGIL 86_ PPLMQ 91_ KTTTL 96_ ALMFG 101_ LYEDL 106_ SCLLR 111_ KHVRA 116_ PEFAT 121_ HGVAA 126_ VLAGT 131_ AEAIF 136_ TPLER 141_ VQTLL 146_ QNHKH 151_ HDKFT 156_ NTYQA 161_ FKALK 166_ CHGIG 171_ EYYRG 176_ LVPIL 181_ FRNGL 186_ SNVLF 191_ FGLRG 196_ PIKEH 201_ LPTAT 206_ THSAH 211_ LVNDF 216_ IGGGL 221_ LGAML 226_ GFLCF 231_ PINVV 236_ KTRLQ 241_ SQIGG 246_ EFQSF 251_ PKVFQ 256_ KIWLE 261_ RDRKL 266_ INLFR 271_ GAHLN 276_ YHRSL 281_ ISWGI 286_ INATY 291_EFLLK

Protein annotations

Protein functions:

1: Mitochondrial membrane carrier protein that mediates the import of NAD(+) into mitochondria (PubMed:32906142). Compared to SLC25A51, SLC25A52-mediated transport is not essential for the import of NAD(+) in mitochondria (PubMed:32906142). The transport mechanism, uniport or antiport, its electrogenicity and substrate selectivity, remain to be elucidated