Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B (EC 2.4.1.-) (EC 2.4.1.155) (Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase B) (GlcNAc-T Vb) (GNT-Vb) (hGnTVb) (Mannoside acetylglucosaminyltransferase 5B) (N-acetylglucosaminyl-transferase Vb) (N-acetylglucosaminyltransferase IX) (GNT-IX)
1_MITVN 6_ PDGKI 11_ MVRRC 16_ LVTLR 21_ PFRLF 26_ VLGIG 31_ FFTLC 36_ FLMTS 41_ LGGQF 46_ SARRL 51_ GDSPF 56_ TIRTE 61_ VMGGP 66_ ESRGV 71_ LRKMS 76_ DLLEL 81_ MVKRM 86_ DALAR 91_ LENSS 96_ ELHRA 101_ GGDLH 106_ FPADR 111_ MPPGA 116_ GLMER 121_ IQAIA 126_ QNVSD 131_ IAVKV 136_ DQILR 141_ HSLLL 146_ HSKVS 151_ EGRRD 156_ QCEAP 161_ SDPKF 166_ PDCSG 171_ KVEWM 176_ RARWT 181_ SDPCY 186_ AFFGV 191_ DGTEC 196_ SFLIY 201_ LSEVE 206_ WFCPP 211_ LPWRN 216_ QTAAQ 221_ RAPKP 226_ LPKVQ 231_ AVFRS 236_ NLSHL 241_ LDLMG 246_ SGKES 251_ LIFMK 256_ KRTKR 261_ LTAQW 266_ ALAAQ 271_ RLAQK 276_ LGATQ 281_ RDQKQ 286_ ILVHI 291_ GFLTE 296_ ESGDV 301_ FSPRV 306_ LKGGP 311_ LGEMV 316_ QWADI 321_ LTALY 326_ VLGHG 331_ LRVTV 336_ SLKEL 341_ QSNLG 346_ VPPGR 351_ GSCPL 356_ TMPLP 361_ FDLIY 366_ TDYHG 371_ LQQMK 376_ RHMGL 381_ SFKKY 386_ RCRIR 391_ VIDTF 396_ GTEPA 401_ YNHEE 406_ YATLH 411_ GYRTN 416_ WGYWN 421_ LNPKQ 426_ FMTMF 431_ PHTPD 436_ NSFMG 441_ FVSEE 446_ LNETE 451_ KRLIK 456_ GGKAS 461_ NMAVV 466_ YGKEA 471_ SIWKL 476_ QGKEK 481_ FLGIL 486_ NKYME 491_ IHGTV 496_ YYESQ 501_ RPPEV 506_ PAFVK 511_ NHGLL 516_ PQPEF 521_ QQLLR 526_ KAKLF 531_ IGFGF 536_ PYEGP 541_ APLEA 546_ IANGC 551_ IFLQS 556_ RFSPP 561_ HSSLN 566_ HEFFR 571_ GKPTS 576_ REVFS 581_ QHPYA 586_ ENFIG 591_ KPHVW 596_ TVDYN 601_ NSEEF 606_ EAAIK 611_ AIMRT 616_ QVDPY 621_ LPYEY 626_ TCEGM 631_ LERIH 636_ AYIQH 641_ QDFCR 646_ APDPA 651_ LPEAH 656_ APQSP 661_ FVLAP 666_ NATHL 671_ EWARN 676_ TSLAP 681_ GAWPP 686_ AHALR 691_ AWLAV 696_ PGRAC 701_ TDTCL 706_ DHGLI 711_ CEPSF 716_ FPFLN 721_ SQDAF 726_ LKLQV 731_ PCDST 736_ ESEMN 741_ HLYPA 746_ FAQPG 751_ QECYL 756_ QKEPL 761_ LFSCA 766_ GSNTK 771_ YRRLC 776_ PCRDF 781_ RKGQV 786_ALCQG
1: Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAc-beta1,2-Man-alpha on both the alpha1,3- and alpha1,6-linked mannose arms in the core structure of N-glycan. Also acts on the GlcNAc-beta1,2-Man-alpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adhesion and migration of neuronal cells via its activity in the O-mannosyl glycan pathway